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As found on Page 504 of the Pearson Human Anatomy and Physiology Laboratory Manual 9th edition.

The redness or flare observed after mechanical stimulation of the skin results from a local inflammatory response promoted by chemical mediators released by injured tissues.

These mediators stimulate increased blood flow into the area and leaking of fluid (from the capillaries) into the local tissues.

Note about an extremely sensitive skin condition:

Dermatographism: a condition in which the direct line of stimulation will swell quite obviously is called a "wheal".

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This results from a local inflammatory response promoted by chemical mediators released by injuries.

pg 504 Human anatomy and physiology lab manual

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Q: Explain the mechanism by which mechanical stimulation of the skin produces a flare?
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