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CSF is produced in the choroid plexus of each ventricle. The choroid plexus is composed of ependymal cells and the cappilaries within the pia mater. CSF is derived from blood plasma. Simular except they differ in ion concentrations. CSF has to be pure of any chemicals or drugs to be allowed to touch the brain. The choroid plexus filters the blood plasma secreted by the ependymal cells to coat the CNS and add buyoancy. CSf starts as blood. The heart pumps it up to the choroid plexus where it is filtered of all proteins, lipids, chemicals, heavy ions, and any other formed elements in blood and waste products in plasma. Once it is collected in the choroid plexus of the lateral ventricles, it goes down into the third ventricle via the cerebral aqueduct and into the fourth ventricle. From the fourth ventricle it exits through either the lateral aperature or the median aperature located on the roof of the fourth ventricle. That exit leads to the subarachnoid space and it coats the CNS removing wastes, adding nutrients, and provididng buoyancy and stability for the brain. CSF enters thearachnoid villi and by force of pressure a on the CSF it is allowed to enter the dural venuouss sinuses without permitting any venuous blood to enter the subarachnoid space. The dirty plasma leaves and enters the blood stream to be filtered by the kidneys and secreted in urine.

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