Acetyl CoA
Pyruvate is converted to acetyl-CoA before entering the Krebs cycle.
During glucose catabolism pyruvat eis produced. This three carbon molecule is broken down to acetyl Co A by the pyruvate decarboxylase reaction. The acetyl Co A feeds the Krebs cycle.
During pyruvate processing
Pyruvate is formed from glucose during glycolysis. Should the conditions be aerobic, pyruvate will be converted into Acetyl Coenzyme A (CoA) with the help of an enzyme called "pyruvate dehydrogenase." Bi-products of this reaction include CO2 and NADH This occurs in the matrix of the mitochondria. Acetyl CoA will then continue into the Krebs cycle/citric acid cycle. After this, the products of the cycle (NADH and FADH2) will be involved in oxidative phosphorylation and the electron transport chain where large amounts of ATP will be produced. This occurs in the inner layer of the mitochondria. Should there be anaerobic conditions, then animals can convert pyruvate into lactate. Or, in plants; pyruvate is converted into ethanal and then into ethanol in a process called fermentation.
Glucose enters the cell by the glucose transporters. It is then broken down to make ATP in two pathways. Anaerobic metabolism is when oxygen is not required. This is also known as glycolysis which takes place in the cytoplasm.
acetyl CoA
pyruvate is con verted into ethanol and carbon dioxide
Each glucose molecule is converted to two molecules of pyruvate through glycolysis. Each molecule of pyruvate can then be converted to 1 acetyl CoA for a total of 2 acetly groups from 1 glucose
In humans, pyruvate cannot be directly converted into glucose through a process called gluconeogenesis. This is because humans lack the specific enzymes required to convert pyruvate into glucose. Pyruvate can be converted into lactate or acetyl-CoA, which can then enter various metabolic pathways in the body.
pyruvate is converted into acetyl coA in the mitochondrial matrix
Pyruvate is converted to acetyl-CoA before entering the Krebs cycle.
Proteins are usually used for structural and enzymic purposes and only broken down when there is an excess or during starvation. When there's an excess of proteins, proteins can be broken down and converted (depending on its structure) into acetyl-CoA, pyruvate or oxaloacetate. Acetyl-CoA is usually used for fat synthesis and pyruvate and oxaloacetate can undergo gluconeogenesis, making glucose in the process. However, fat is a much more efficient storage molecule. During starvation, proteins are broken down as a last effort to provide nutrients, and the acetyl-CoA, pyruvate and oxaloacetate generated are usually used directly in the Krebs cycle. However, in the liver where more nutrients are stored, gluconeogenesis can still occur to provide glucose for the rest of the body.
When glucose is converted into energy, it is broken down into pyruvate and then acetyl-CoA. If energy is required, the acetyl-CoA will enter the Citric Acid Cycle and be used to make ATP. However, if you are not active, then the acetyl-CoA is converted into fat for storage.
Fats and proteins are brought into the Krebs cycle by being converted. They can either be converted to glucose or acetyl which will go through Krebs cycle.
During glucose catabolism pyruvat eis produced. This three carbon molecule is broken down to acetyl Co A by the pyruvate decarboxylase reaction. The acetyl Co A feeds the Krebs cycle.
Pyruvate is an organic acid and is a ketone functional group. It is made up of glucose, acetyl co enzyme A, alanine, and ethanol.
In the decarboxylation of Pyruvate to form Acetyl CoA, one Carbon atom is lost as co2. Acetyl CoA can then be used in the citric acid cycle in which another two co2 molecules are produced. It is important to note however, that neither Pyruvate nor Acetyl CoA will necessarily follow this pathway, since they are also required for various other processes.