How does resistance to vancomycin occur?

Answer 1

any trait that is possessed by a creature with a plasmid dna loop can inherit genes from both division and error replication and from absorption of Rna and Dna from the environment, this means a organism can grab this immunity from the environment it exists in, if the material is present so just by the nature of these creatures, beneficial traits are passed on after death, or by mutation, another method of immunity is to go into a stasis or spore mode, and out wait the offending attacker, hatch, and wreak havoc when you have the element of surprise, like the spore forming rods, another way they can evade is by inhabiting a region inaccessible to the antibiotic like inside of a bone or in the brain, like lyme disease and other spiral organisms,

Answer 2

Resistance to vancomycin can occur through several mechanisms, including modifications in the cell wall structure (e.g., altered peptidoglycan synthesis), production of enzymes that modify vancomycin, or acquisition of resistance genes through horizontal gene transfer. The most common mechanism is the alteration of the target site on the bacterial cell wall that vancomycin binds to, making the antibiotic less effective.