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OI is a genetic disease. The inheritance pattern is usually autosomal dominant. This means an affected person will have OI even though only one faulty gene has been passed along. This faulty gene can come from either parent, and it can affect either sex. Each child of an affected parent will have a 50 percent chance of developing OI.
Occasionally, a person will develop OI even though neither parent carried the faulty gene. This is called a spontaneous mutation. A person who develops OI will have the same chance of passing it on to a child as does someone who inherited the autosomal dominant gene.
It is important for you to understand that nothing you or your spouse did during conception or pregnancy caused this condition in your child. OI has been prevalent for thousands of years. Genetic counseling, which is available at most hospitals, may help you understand.
What else can I help you with?
What are some diseases caused by the bone cell?
Some diseases caused by bone cells include osteoporosis (bone density loss), osteogenesis imperfecta (brittle bones), and Paget's disease (abnormal bone remodeling). These conditions can lead to increased fractures, deformities, and pain in affected individuals.
Is Brittle Bone Disease genetic?
Yes, Brittle Bone Disease, also known as Osteogenesis Imperfecta, is a genetic disorder. It is caused by a gene mutation that affects the body's ability to produce collagen, resulting in brittle and fragile bones that are prone to fractures. The severity of the condition can vary depending on the specific gene mutation involved.
What causes blue sclera in osteogenesisis imperfecta?
The underlying deficiency in OI is a defective Type I Collagen. Because this doesn't form correctly the sclera ends up being thinner than normal. This makes it easier to see the underlying choroidal veins which give them a blue-gray coloration.
What is poor formation of bone called?
this is the complex term.pathology depends on the factor .for eg...congenital malformation of bone is called as dysostoses.
The most common bone disease is?
There are quite a few disease that can affect the bones in your body. I will name the top 3. They are Osteoporosis, Osteogenesis imperfecta, and Paget's disease. A short description of the three are listed below:1.) Osteporosis, is the most commonly known one, this affects people of all ages, but is common in older women. Osteoporosis, as defined by Google Health, is the thinning of bone tissue and loss of bone density, or when the bone simply just gets too old and the body fails to produce enough new bone. 2.) Osteogenesis imperfecta is a condition that causes extremely fragile bones. This disease is known an congenital, meaning it occurs at birth.3.) Paget's Disease is a chronic bone condition that is characterized by disorder of the normal bone remodeling process. This disease is most common in older adults. Paget's Disease is rarely found in children, mainly just adults. Bone diseases may come in different names. But basically, all of it involves the break down or weakening of the bone tissues in the body. there is basically, many bones.The diseases of bones are:Rickets,Osteoporosis,Scolios,Arthritis and Bone Infections.osteoporosis, cancer, osteogenisis imperfecta, Paget's disease, Rickets, osteonecrosis.Heres some of umBone cystBone spur (Osteophytes)Bone tumorCraniosynostosisFibrodysplasia ossificans progressivaFibrous dysplasiaGiant cell tumor of boneHypophosphatasiaKlippel-Feil syndromeMetabolic Bone DiseaseOsteitis deformans (or Paget's disease of bone)Osteitis fibrosa cystica (or Osteitis fibrosa, or Von Recklinghausen's disease of bone)Osteitis pubisCondensing osteitis (or Osteitis condensans)Osteitis condensans iliiOsteochondritis dissecansOsteochondroma (Bone Tumor)Osteogenesis ImperfectaOsteomalaciaOsteomyelitisOsteopeniaOsteopetrosisOsteoporosisOsteosarcoma (Bone Tumor)Porotic hyperostosisPrimary hyperparathyroidismRenal Osteodystrophy
What countries are at risk of osteogenesis imperfecta?
USA
What calcuim does for the body?
Lack of calcium can lead to Osteogenesis Imperfecta
What causes blue sclerae in osteogenesis imperfecta?
Type I Osteogenesis Imperfecta is the most common and mildest type of this disease. In this type the Scleras (whites of the eyes) usually have a blue, purple, or gray tint.
What causes Craniotabes?
premature infants(as normal finding),rickets,osteogenesis imperfecta
Do you have to be born with osteogenesis imperfecta to have it?
Yes, because it is a genetic disease you inherit from your parents.
What is the difference between osteogenesis imperfecta and osteoporosis?
Osteoporosis occurs later in life and leads to weakening and fractures of the bones. Osteogenesis imperfecta is a congenital defect which causes fractures to occur from the slightest bump or touch in a child.
Where was osteogenesis imperfecta discovered?
Osteogenesis imperfecta, also known as brittle bone disease, was first described by British surgeon John F. Clarke in 1695. He observed patients with fragile bones that easily fractured, leading to the recognition of this genetic disorder.
What are some of the symptoms of osteogenesis imperfecta?
Osteogenesis imperfecta is a genetic disorder that causes brittleness of one bones. This can cause ones bones to break easily and even for no apparent reason. Also, it can lead to abnormally large amounts of repair tissue at the site of fractures.
Can babies be born with bone fractures or bone diseases causing them?
osteogenesis imperfecta - brittle bone disease
What is the medical term meaning poor development of bones?
Osteogenesis imperfecta means poor development of bones.
How tall can you be with osteogenesis imperfecta?
"some people may only grow to be three feet tall"sourcehttp://www.orthop.washington.edu/?q=patient-care/articles/arthritis/osteogenesis-imperfecta.html
What has the author Jenny Ford written?
Jenny Ford has written: 'An investigation into voice quality in eight individuals with osteogenesis imperfecta'
