How is the loss of contact inhibition related to tumor formation?

Answer 1

The average normal cells cease splitting up when they get to contact with their adjacent cells, resulting to only needed number of cells split up and stop when not needful.Therefore if cells do lose this feature, they don't terminate splitting up when they come to contact with each other. They constantly increase or multiply rapidly because contact inhibition isn't present hence resulting to tumor formation.

Answer 2

Loss of contact inhibition is a hallmark of cancer cells, allowing them to continue growing and dividing uncontrollably even in the absence of external signals. This loss of regulation can lead to the formation of tumors as cells ignore normal boundaries and proliferate in an uncontrolled manner. The disruption of contact inhibition enables cancer cells to invade surrounding tissues and metastasize to other parts of the body.