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It depends on the size of the point of the instrument doing the puncturing (i.e. a needle takes only a little force, but a bullet takes quite a bit). What you really need is how much pressure does it take to puncture skin. I don't believe there is a tested exact amount of pressure required to pierce human skin. One theoretical number taken from the paper linked below is:

(3.183 x10^6 Pa)this is bull **** the femur can't take that much its is really 20000Pa 461.7 PSI (Pounds per square inch)

http://csdl2.computer.org/persagen/DLAbsToc.jsp?resourcePath=/dl/proceedings/&toc=comp/proceedings/icmens/2003/1947/00/1947toc.xml&DOI=10.1109/ICMENS.2003.1221960

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Q: How much force is needed to puncture average human skin?
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