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DNA was discovered by a Swiss scientist, Friedrich Miescher, in 1869.

In 1953 James Watson and Francis Crick proposed the double-helix structure for the molecule, and by 1966 the genetic code (i.e. which amino acids were coded for by which sequences of DNA bases, and what the remaining codons "meant", ) had been completely worked out.

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While examining the DNA molecule, Watson and Crick (1953), proposed a satisfactory model for the arrangement of these constituents. For this important contribution to science they were given the 1962 Nobel Prize. They hypothesized from X-ray analysis of the molecule that DNA consists of two strands, twisted in a spiral (or helix) shape. This shape resembles a twisted ladder with rungs between the two uprights. The "uprights" of this ladder are made entirely of alternating phosphate and sugar molecules. The rungs are composed only of the nitrogen bases, which are attached to the sugar. The phosphate-sugar-base is called a nucleotide. The base of the nucleotide from one "upright" of the ladder is paired with and bonded to the base of the nucleotide from the other side of the ladder, completing the rung between the two uprights. A nucleotide having adenine is always cross-paired with thymine, and one with cytosine is always bonded to guanine.

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What year was DNA discovered?

DNA was discovered in 1869 by Friedrich Miescher, a Swiss biologist who isolated it from the nuclei of white blood cells. However, the significance of DNA as the carrier of genetic information was not fully understood until the mid-20th century, when the structure of the DNA molecule was elucidated by James Watson and Francis Crick in 1953.


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