Yes.
"Smooth ER also is involved in the uptake and release of calcium to mediate some types of cellular activity. In skeletal muscle cells, for example, the release of calcium from the smooth ER triggers muscle contraction." Source: http://encarta.msn.com/encyclopedia_761587444/Endoplasmic_Reticulum.html
An inhibitor of ryanodine receptors could be used to block the release of calcium from the endoplasmic reticulum. Ryanodine receptors are calcium release channels located on the endoplasmic reticulum membrane that play a key role in releasing stored calcium into the cytoplasm. Blocking these receptors can prevent the release of calcium and subsequent downstream signaling events.
The sarcoplasmic reticulum in muscle fiber corresponds to the endoplasmic reticulum in other cell types. The sarcoplasmic reticulum is a specialized type of endoplasmic reticulum found in muscle cells, and it plays a key role in calcium storage and release during muscle contraction.
The portion of the endoplasmic reticulum that lacks attached ribosomes is called smooth endoplasmic reticulum (SER). It is involved in lipid metabolism, detoxification of drugs and toxins, and calcium storage and release in muscle cells.
The endoplasmic reticulum has a store of calcium ions, Ca 2+, that it releases as second messengers in signalling transduction. Also the scarcoplasmic reticulum releases this ion in the process of sarcomere contraction.
The main function of smooth endoplasmic reticulum is to synthesize lipids, including phospholipids and steroids, and to detoxify drugs and other harmful substances in the cell. It also stores calcium ions and helps regulate their release in muscle cells.
The endoplasmic reticulum is specialized for the storage and release of calcium. This organelle has calcium pumps that actively transport calcium ions into its lumen for storage, and calcium channels that release calcium into the cytoplasm during cell signaling processes.
An inhibitor of ryanodine receptors could be used to block the release of calcium from the endoplasmic reticulum. Ryanodine receptors are calcium release channels located on the endoplasmic reticulum membrane that play a key role in releasing stored calcium into the cytoplasm. Blocking these receptors can prevent the release of calcium and subsequent downstream signaling events.
The sarcoplasmic reticulum in muscle fiber corresponds to the endoplasmic reticulum in other cell types. The sarcoplasmic reticulum is a specialized type of endoplasmic reticulum found in muscle cells, and it plays a key role in calcium storage and release during muscle contraction.
The portion of the endoplasmic reticulum that lacks attached ribosomes is called smooth endoplasmic reticulum (SER). It is involved in lipid metabolism, detoxification of drugs and toxins, and calcium storage and release in muscle cells.
The endoplasmic reticulum has a store of calcium ions, Ca 2+, that it releases as second messengers in signalling transduction. Also the scarcoplasmic reticulum releases this ion in the process of sarcomere contraction.
The integral proteins of the sarcoplasmic reticulum (SR) are primarily known as ryanodine receptors (RyRs). These proteins play a crucial role in calcium release during muscle contraction. Additionally, the SR contains other integral proteins such as the sarco/endoplasmic reticulum calcium ATPase (SERCA), which is responsible for pumping calcium back into the SR after contraction.
Calcium ions that act as second messengers are typically stored in the endoplasmic reticulum or the extracellular space. When a signaling event triggers their release, they can quickly enter the cytoplasm to transmit the signal.
Most likely the mitochondria (with respect to oxidative stress and apoptosis) and the endoplasmic reticulum.
The main function of smooth endoplasmic reticulum is to synthesize lipids, including phospholipids and steroids, and to detoxify drugs and other harmful substances in the cell. It also stores calcium ions and helps regulate their release in muscle cells.
The smooth endoplasmic reticulum is a vast network of membrane-bound vesicles and tubules. It does the following: 1. lipid and steroid hormone synthesis 2. breakdown of lipid-soluble toxins in liver cells 3. control of calcium release in muscle cell contraction
The calcium would come from the sarcoplasmic reticulum, which is a specialized structure found within skeletal muscle cells responsible for storing and releasing calcium ions for muscle contraction. A sudden release of large amounts of calcium from the sarcoplasmic reticulum can lead to uncontrolled muscle contractions and potentially muscle damage.
The structure responsible for storing calcium in skeletal muscle fibers at rest is the sarcoplasmic reticulum. This organelle regulates the release of calcium ions during muscle contraction to trigger the muscle fiber to contract.