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Chromosomal mutation

AneuploidyAneuploidy occurs when a cell has the wrong number of chromosomes either due to an extra or missing chromosome. This type of problem can occur during the anaphase part of M phase. Through a process called nondisjunction the chromosome pairs may not separate properly causing one of the daughter cells to receive both copies of a chromosome and the other daughter cell receives no copies of that chromosome. Therefore, one daughter cell will have an extra chromosome and the other daughter cell will have a missing chromosome. Also, this problem can occur if there is a lag during anaphase. When the pairs of chromosomes separate to each side of the cell, a chromosome may travel too slow which would cause it to not be incorporated into the new cell. This new cell would be missing a chromosome.

Deletion

Chromosome Deletions occur when the cell is missing a portion of a chromosome. This type of problem can occur during S phase if there is a problem during DNA replication or other parts of interphase if the DNA is damaged.

Duplication

Chromosome Duplications occur when a cell has a repeated portion of a chromosome which causes the cell to have extra information. This type of problem can occur during S phase if there is a problem during DNA replication.

Inversion

Chromosome Inversions occur when a piece of a chromosome breaks and that piece is reattached in the opposite orientation. This type of problem can occur during interphase if the DNA is exposed to damage that causes DNA breakage.

Insertion

Chromosome Insertions occur when a piece of a chromosome that had broken reattaches in a location where this genetic material is not typically found. This type of problem can occur during interphase if the DNA is broken and then repaired by attaching to a different location.

Translocation

There are two types of translocations: reciprocal and robertsonian. A reciprocal translocation occurs when two nonhomologous chromosomes break and then switch genetic material. A robertsonian translocation occurs when two chromosomes break on the p arm near the centromere and then the two q arms attach together while the p arms are lost. Either of these types of translocation can occur at any point during the cell cycle.
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Q: Mutation that occurs at the chromosome level resulting in changes in the gene distribution?
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How do chromosome mutation bring evolutionary changes?

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What mutation cause changes in the number of chromosome?

Aneuploidy mutation causes a change in the number of chromosomes. Aneuploidy occurs during cell division when the chromosomes do not separate properly resulting in a change in the number of chromosomes.


How do chromosome mutations affect an individual?

Chromosome mutations can result in changes in the number of chromosomes in a cell or changes in the structure of a chromosome. Unlike a gene mutation which alters a single gene or larger segment of DNA on a chromosome, chromosome mutations change and impact the entire chromosome.


What is the definition of chromosome mutation?

A chromosome is an organized structure of DNA and protein that is found in cells.In biology, mutations are changes to the nucleotide sequence of the genetic material of an organism.


Could a mutation in a cell in the liver of a human be passed on?

For a mutation to be passed onto the next generation it must be on sex chromosome. If mutation occurs in somatic cells of our body, it will not be passed on to the offspring(s). Mutation that changes one or few base pairs in the DNA is called point mutation.


Summarise the causes of gene and chromosome mutation and suggest how these changes can bring about evolutionary changes by the process of selection using named examples?

http://wiki.answers.com/Q/Summarise_the_causes_of_gene_and_chromosome_mutation_and_suggest_how_these_changes_can_bring_about_evolutionary_changes_by_the_process_of_selection_using_named_examples"


Changes in a DNA sequence that affect an entire chromosome or multiple chromosomes?

The DNA sequence of an entire chromosome is affected by a nitrogen base. A mutation is any mistake or change in the DNA sequence.


Chromosomal mutation resulting in alagille syndrome?

Alagille syndrome is predominately caused by changes in a gene called Jagged1 located on chromosome 20. The effects vary widely from severe Alagille syndrome, involving heart and liver disease, to others experiencing only minor manifestations.


What are 4 types of chromosome structural changes?

The four types of alterations of chromosome structure are deletion, duplication, inversion, and reciprocal translocation. Deletion is the loss of one or more nucleotides from a gene by mutation; the loss of a fragment of a chromosome. Duplication is repition of a part of a chromosome resulting from fusion with a fragment froma homologous chromosome. Duplication can result from an error in meiosis or from mutagenesis. Inversion is a change in a chromosomeresulting from reattachment of a chromosome fragment to the original chromosome, but in a reverse direction. Mutagens and errors during mesosis can cause inversions. Translocation is the attachment of a chromosomal fragment to a nonhomologous chromosome.


What is the difference between a nonsense mutation and a missense mutation?

Missense mutation: changes one sense codon to another, resulting in incorporation of amino acid.Nonsense mutation: changes a sense codon into a stop (or nonsense) codon, resulting in premature termination.


What is the difference between mutation and evolution?

Evolution= the major transition from one type of organism to another occurring at the level of the species and higher taxa. Mutation= a sudden departure from the parent type in one or more heritable characteristics, caused by a change in a gene or a chromosome. in other words, evolution is when a horse gives birth to a chicken. etc... and mutation is when a gene or a chromosome changes. hope this helped


What is the difference between gene and chromosomal mutation?

A gene mutation is a permanent change in the DNA sequence that makes up a gene. Mutations range in size from a single DNA building block (DNA base) to a large segment of a chromosome. A chromosomal mutation is a mutation involving a long segment of DNA, it is a any change in the structure or arrangement of the chromosomes. These mutations can involve deletions, insertions, or inversions of sections of DNA. In some cases, deleted sections may attach to other chromosomes, disrupting both the chromosomes that loses the DNA and the one that gains it.It is also referred to as a chromosomal rearrangement The differences between Gene mutation and Chromosome mutation are ; 1- Chromosome mutations involve changes in the structure of a chromosome OR the loss or gain of a chromosome while Gene mutations involve a change in the nucleotide -base sequence of a gene on a DNA molecule. 2- Chromosomal mutations are changes in the structure or the numbers of chromosomes (a gain or loss). Gene mutations involve changes in the nucleotide sequence of the DNA molecule. 3-A gene mutation is a permanent change in the DNA sequence that makes up a gene. Mutations range in size from a single DNA building block (DNA base) to a large segment of a chromosome while a chromosomal mutation is a mutation involving a long segment of DNA, it is a any change in the structure or arrangement of the chromosomes. These mutations can involve deletions, insertions, or inversions of sections of DNA. In some cases, deleted sections may attach to other chromosomes, disrupting both the chromosomes that loses the DNA and the one that gains it.It is also referred to as a chromosomal rearrangement 4-gene mutation is just a substitute in any old random nucleotide for any old random nucleotide chromosome mutation is missing of chromosome or +1 chromosome (down's syndrome).