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Both occur at the Replication Fork.

Don't let the name deceive you.

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Replication that occurs between sites is called?

intersite replication


Where does DNA replication begin-?

The DNA replication machinery initially assembles and begins replication at the origin of replication. It contains high levels of AT base pairs for easier unzipping and there's usually one per bacteria chromosome, several for archaea chromosome, and many many more for eukaryotic linear chromosomes.


What binds to the prokaryotic chromosome to start DNA replication?

In prokaryotes, the DNA replication process is initiated by the binding of the DnaA protein to specific sites on the bacterial chromosome called DnaA boxes. DnaA protein helps in unwinding the DNA strands to enable replication to start.


What is the foundation of DNA replication?

Before duplication, aptly named initiator proteins bind to DNA at replication initiation sites and break the bonds holding the complementary base pairs together, separating the double helix locally into single strands and creating two Y-shaped junctions at either end called replication forks. At each replication fork, a complex of proteins continues the business of unzipping the DNA and using the exposed single strands as templates to generate complementary daughter strands. What controls when and how individual initiation sites are activated in mammalian cells has remained obscure. Is initiation restricted to specific sites? Do specific DNA sequences control initiation events locally? Examining individual molecules of fluorescently labeled replicating DNA, Paolo Norio and Carl Schildkraut report that initiation events are not controlled by individual initiation sites but occur throughout the genome. And the activation of these sites appears to depend on what's happening at the genomic level. Norio and Schildkraut studied replication using two strains of the EBV virus grown in human B cells, their natural target. Previous studies, which had largely focused on the activity of individual initiation sites, had suggested that different EBV strains vary in how initiation sites are activated and that specific initiation sites or regions likely regulate replication. Looking at larger genomic regions, Norio and Schildkraut found something different: not only do initiation sites occur throughout the genomes, but their activity "differs dramatically" in the two EBV strains and even within a strain. Differences were seen in the order of initiation site activation, in the direction of replication fork movement, and in the speed of duplication in different parts of the genome. While the two largely similar viral genomes do show some genetic differences, the authors dismiss the idea that these local differences could explain the observed variations in replication control. It's more likely, they conclude, that epigenetic modifications (such as changes in chromatin structure) produce the differences in the order and frequency of activation of initiation sites across genomic regions. It seems that initiation events are not restricted to specific genomic areas, and experimentally induced loss of individual initiation sites does not significantly affect EBV genome replication (because other sites take up the slack). This redundancy provides flexibility in determining which sites are activated. Since the EBV genome uses human replication machinery to duplicate its genome, these findings likely apply to DNA replication in mammalian cells as well. The very survival of the cell-and the health of the organism it inhabits-depends upon the faithful replication of the genome. Using processes that operate at the genomic level may afford cells the means to manage an unwieldy genome, and perhaps, more importantly, guarantee their genes safe passage to the next generation.


How does the ecor1 cut affect the process of DNA replication?

The EcoR1 cut can disrupt the process of DNA replication by cleaving the DNA at specific sites, potentially causing errors in the replication process. This can lead to mutations or changes in the genetic information being copied.

Related Questions

The sites where DNA replication and separation occur are called what?

in the cytoplasm!


Replication that occurs between sites is called?

intersite replication


What is intersite replication?

Replication between two sites is known as Intersite Replication. Since bandwidth two different sites is usually very limited, so intersite replication is used to manage and control replication traffic.


What is intersite?

Replication between two sites is known as Intersite Replication. Since bandwidth two different sites is usually very limited, so intersite replication is used to manage and control replication traffic.


What is the site of DNA replication in eukaryotes?

The site of DNA replication in eukaryotes is the nucleus. Replication occurs in the nucleus because this is where the DNA is stored. The process involves unwinding the DNA double helix and synthesizing new strands of DNA using the existing strands as templates.


Where does DNA replication begin-?

The DNA replication machinery initially assembles and begins replication at the origin of replication. It contains high levels of AT base pairs for easier unzipping and there's usually one per bacteria chromosome, several for archaea chromosome, and many many more for eukaryotic linear chromosomes.


What are sites of origin?

Within the Bacterial context: they are the unique sites - called Ori-C - on a [circular] Chromosome that perform this function. In eukaryotes, the origin of Replication occurs at several [due to the size] distinct locales.


What is the advantage to the multiple sites of replication along the DNA molecule?

I am sitting by Kelby L. ^ what kind of answer is that? The advantage to having multiple sites of DNA replication is basically to quicken the process of DNA replication Why the process needs to be quicken... im not too sure...


Why Active Directory is called active?

Active Directory is called active bacause it is actively updating it's data through replication from differnt sites and other domain controllers with in the network


Domain controllers located in different sites will participate in intrasite replication?

Only one domain controller will be used per site to replicate to another site(process called as intersite replication) it could be a bridge head server(selected DC to do replication from the site)or DC selected by ISTG protocol if enabled. there would be lot of DCs in intrasite replication within a site.


True or false Domain controllers located in different sites will participate in intrasite replication?

False Only one domain controller will be used per site to replicate to another site(process called as intersite replication) it could be a bridge head server(selected DC to do replication from the site)or DC selected by ISTG protocol if enabled. there would be lot of DCs in intrasite replication within a site.


What binds to the prokaryotic chromosome to start DNA replication?

In prokaryotes, the DNA replication process is initiated by the binding of the DnaA protein to specific sites on the bacterial chromosome called DnaA boxes. DnaA protein helps in unwinding the DNA strands to enable replication to start.