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The c-terminus and n-terminus of a protein are two distinct regions. The n-terminus is the starting point of a protein chain, while the c-terminus is the end point. Functionally, the n-terminus often plays a role in targeting the protein to specific locations within the cell, while the c-terminus can be involved in protein-protein interactions and signaling pathways. Structurally, the n-terminus tends to be more flexible and exposed, while the c-terminus is often more rigid and buried within the protein's structure.

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