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When an inhibitor closely resembles another molecule, it can interfere with the normal functioning of biological processes by binding to the same target molecules. This can disrupt important pathways and lead to changes in cellular functions.

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5mo ago

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What statement best describes the function of a competitive inhibitor in an enzyme-catalyzed reaction?

Competitive inhibitor is a substance that competes directly with a normal substrate for an enzymatic-binding site of an enzyme. Such an inhibitor usually resembles the substrate to the extent that it specifically binds to the active site of the enzyme but differs from it so as to be unreactive and therefore there will be no catalytic reaction. Some examples are: methotrexate that is competitive inhibitor of dihydrofolate reductase, and malonate which structurally resembles succinate (that is converted to fumarate by succinate dehydrogenase during the citric acid cycle) but cannot be dehydrogenated.


What inhibitor has a structure that is so similar to the substrate that it can bond to the enzyme just like the substrate?

A competitive inhibitor has a structure that closely resembles the substrate, allowing it to bind to the enzyme's active site in a similar manner. This competition between the inhibitor and substrate for the active site directly affects the enzyme's ability to catalyze reactions.


How malonate inhibit the conversion of succinate to fumarate?

Malonate is a competitive inhibitor of succinate dehydrogenase, the enzyme responsible for converting succinate to fumarate in the citric acid cycle. Malonate resembles succinate and competes for the active site of succinate dehydrogenase. As a result, malonate binds to the enzyme and prevents succinate from binding, inhibiting the conversion of succinate to fumarate.


What is the significance of the flag that resembles Puerto Rico in terms of cultural representation and identity?

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