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Microsatellites and minisatellites are both types of repetitive DNA sequences that are found in the genome. They are both composed of short repeating units of nucleotides, but microsatellites have shorter repeat units (usually 1-6 base pairs) compared to minisatellites, which have longer repeat units (usually 10-100 base pairs).

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5mo ago

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What are the differences between minisatellites and microsatellites?

They are usually distinguished according to the size of the repeats: Microsatellites, also termed Short tandem repeats (STRs) consist of tracts of repeats of 1-7bp, and minisatellites also called (VNTR) usually contain repeats of longer length (100-several hundred bp) Minisatellites can be found in tandem arrays, but the majority are interspersed in the genome. Whilst microsatellites are found mostly in tandem repeats.


What are the key differences between SNPs and microsatellites in terms of their utility for genetic analysis?

Single nucleotide polymorphisms (SNPs) are variations in a single nucleotide in the DNA sequence, while microsatellites are short, repetitive sequences of DNA. SNPs are more abundant in the genome and are easier to analyze, making them more commonly used in genetic studies. Microsatellites have higher mutation rates and are useful for studying genetic diversity and population genetics.


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