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AIDS.
Yes
Blood (serum) is often used only to detect HIV and Hepatitis. Other STDs, such as genital herpes, can be detected by looking for your system's antibodies to that specific virus, but these tests are not often used.

Bacterial and viral STDs are most often tested for by either using a swab taken from the genitals, or by urine.
HIV - Human Immunodeficiency Virus

Or

AIDS - Acquired Immunodeficiency Syndrome

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