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The 4 phases of a typical cell cycle and the events occurring during each phase are outlined:

1. Mitotic phase (or) M phase:

This is the initial stage when cells prepare for and then undergo the process of cytokinesis. M phase is simply termed as 'mitosis' also. During mitosis the chromosomes are paired and then divided prior to cell division. The events in this stage of the cell cycle leading to cell division are prophase, metaphase, anaphase and telophase. All these four stages have their own significance.

2. G1phase:

This stage corresponds to the gap in the cell cycle which follows cytokinesis. During this phase, the cells make a decision to either exit the cell cycle or become dormant or terminally differentiated or to continue dividing.

Terminal differentiation is identified as a non-dividing state for a cell. Dormant and terminally differentiated cells are identified as being in G0phase. Cells in G0 can remain in this state for extended periods of time without division.

Specific stimuli may induce the G0 cell to re-enter the cell cycle at the G1 phase or alternatively may induce permanent terminal differentiation.

During G1 phase, cells begin synthesizing all the cellular components needed in order to generate two identically complimented daughter cells. As a result the size of cells begins to increase during G1.

3. S phase:

This is an important stage of the cell cycle during which the DNA is replicated. This is the DNA synthesis phase. Additionally, some specialized proteins like histones are also synthesized during S phase.

4. G2 phase: This is the final stage after the completion of DNA replication.

During G2 phase,

i. Chromosomes begin to condense

ii. Nucleoli disappear

iii. Spindle pores are produced.

Typical eukaryotic cell cycles take up approximately 16 - 24 hrs when grown in culture. However, in the context of the multicellular organization of organisms the cell cycles can be as short as 6 - 8 hrs to as much greater as 100 days.

The G1 phase of the cycle leads to this high variability of cell cycle durations. Source: www.examville.com
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