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1. Vasodialation and increased permeability of vessels:

Caused by histamines from mast cells, kinins from precursors in the blood, prostoglandins from damages cells and leukotrienes from basophils and mast cells.

Blood flow increases, extra clotting factors, antibodies localize.

2. Phagocyte Emigration:

Occurs within one hour, neutrophils and then monocytes arrive and leave the blood stream(emigration) as a result of chemotaxis.

3. Initiation of Tissue Repair:

Neutrophils and macrophages (short life span) die and form pus. This begins the tissue repair process. Pus eventually drains.

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