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To grow or multiply by rapidly producing new tissue, parts, cells, or offspring

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Jessie Zieme

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3y ago

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What is the the role of cyclic AMP in cell proliferation?

Cyclic AMP is a secondary messenger that regulates cell proliferation by activating protein kinase A (PKA). PKA then phosphorylates target proteins involved in cell cycle progression, gene expression, and other cellular processes that drive cell proliferation. Overall, cyclic AMP signaling pathways play a crucial role in coordinating the cell's response to proliferative signals.


How do you relate O.D values of MTT assay to cell count?

Data Interpretation for an MMT assay: Absorbance (OD) values that are lower than the control cells indicate a reduction in the rate of cell proliferation. Conversely a higher absorbance rate indicates an increase in cell proliferation. Rarely, an increase in proliferation may be offset by cell death; evidence of cell death may be inferred from morphological changes.


What is spindle cell proliferation?

Spindle cells are what make up the body's connective tissue, fat, muscle, bone, cartilage, and blood vessels. Proliferation is fibroplastic response in granulomatous inflammation, which may be hard to tell if it is benign or malignant neoplasms.


What is epidermopoiesis?

Epidermopoiesis is the process of epidermal cell development and differentiation in the skin. It involves the proliferation and maturation of keratinocytes, the main cells of the epidermis, leading to the formation of the different layers of the skin.


What is the optimal cell culture plate area for promoting cell growth and proliferation in a laboratory setting?

The optimal cell culture plate area for promoting cell growth and proliferation in a laboratory setting is typically around 6-10 cm per well. This size provides enough space for cells to attach and grow, while also allowing for sufficient nutrient and gas exchange to support their growth.