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The main controls to respiration are levels of C02 and to a much lesser extent oxygen. Since C02 levels reflect both acid-base balance as well as levels of metabolic activity there are two possibilities for lowering respiration rates. One possibility would be ingestion of basic compounds, like Na0H. Think of it as a kind of poisoning...... Another reason would be a decrease in metabolism rates as occurs in thyroid disorders. Another mechanism is by hyperventilation. It is possible to lower CO2 levels by hyperventilation enough to remove all the drive to breath then pass out from lack of oxygen.

Another possibility is that the regulation of breathing has been damaged. This control is mediated in the brain stem so injuries to the head, tumors and drugs can also have an affect on the rate of respiration. Glue sniffing comes to mind, but then an entire range of industrial and home products can also damage neural control of respiration.

How would you distinguish? First test would be to measure blood pH. If the blood is acidic in the face of low respiration rates the next place to look would be in the brain stem.

useful link:respiratory-failure-2

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