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Perforin

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Q: What causes transmembrane channels in target cells?
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Body cells that react to particular hormone are called?

target cells


What is the main cellular target of the HIV virus which causes AIDS?

Helper T cells


What is the cellular abnormality that causes cystic fibrosis?

abnormal chloride channels that trap salt inside cells lining the lung passageways.


What cells are affected by cystic fibrosis?

The protein affected by cystic fibrosis is called the cystic fibrosis transmembrane conductance regulator or CFTR. CFTR acts as a channel that transports negatively charged chloride ions into and out of cells. This helps control the flow of water in tissues. CFTR also regulates the function of other channels that transport positive sodium ions into and out of cells.


What are the target cells of erythropoietin?

The target cells for Erythropoietin are red blood cells


What do scientists currently believe is the cause of Cystic Fibrosis How are the faulty gene inherited and what direct effect does that have on the affected cells?

The faulty gene causes the misfolding of a protein called the Cystic Fibrosis Transmembrane conductance Regulator (CFTR). CFTR is responsible for the movement of chloride and sodium ions into and out of cells. The lack of salt and water on the surface of the cells causes the mucus to become extremely thick and sticky which builds up in and clogs organs.


What causes the rapid change in the resting membranes potential that initiates an action potential?

In muscle cells the inward current is a sodium + calcium flow through acetycholine activated channels as well as through voltage sensitive calcium channels.


What tissue is responsible for transporting carbohydrates from leaves to other parts of the plant?

For tissue that is found in the leaves, transmembrane protein is responsible for transporting carbohydrates from leaves to various parts of the plant . Sugars are taken up by the transmembrane protein with the help of companion cells.


Why blocking the sodium channels result in diarrhoea?

Blocking sodium ion channels reduces the uptake of water from the lumen of the intenstine into the epithelial cells of the villus due to osmosis. Water, therefore, remains in the intestine and this causes watery faeces/diarrhoea


What passes from the neuron to the muscle cells and what effect does it produce?

Acetylcholine (ACh) is the neurotransmitter that passes from neuron to muscle cells and it causes the Na/K channels to open allowing Na+ to flow into the cell triggering an action potential.


Why is it important that capillary cells have channels between them?

for difussion


Why is it important capillary cells channels between them?

for difussion