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The only cells which lack DNA are the mature <b>red blood cells</b> (erythrocytes). This is because they lack a nucleus, which is where the DNA is found in other cells. Red blood cells also lack mitochondria which themselves have DNA. Therefore they not only lack nuclei DNA, but mitochondrial DNA as well. <br /><br /> Red blood cells develop in your bone marrow from special cells called stem cells. These do have a nucleus, but as the red blood cell develops the nucleus is squeezed/taken out. This makes more room for the red pigment haemoglobin, which is needed to carry the Oxygen in the red cells. Haemoglobin also carry's Glucose needed for energy and also they take Carbon Dioxide away from the cells to be breathed out through the lungs

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