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They are mechanoreceptors that detect pressure, and are found in the skin and also in joints and tendons. Naked nerve endings lie in the centre of the corpuscle surrounded by concentric layers of connective tissue separated by viscous gel (looks a little bit like an onion!).

Mechanical stimuli are converted into electrical impulses as follows:

  • Transduction occurs - the production of a small receptor potential of about 1mV across the receptor membrane when pressure is applied.
  • The receptor potential is produced by deformation of the receptor membrane, which interferes with ion channels embedded in the membrane and causes leaks, allowing an influx of sodium ions.
  • A generator potential is produced and an impulse is generated at the first node of ranvier. Electrical impulses are transmitted along the neurone.

The presence of gel-filled lamellae in the Pacinian corpuscles provides a mechanical filter of the stimulus. If pressure is applied rapidly the membrane of the corpuscle is deformed for a few milliseconds until the gel flows and the membrane resumes its normal shape. If pressure is applied slowly the gel flows away from the stimulus so the membrane is not deformed, and no receptor potential is generated. The greater the pressure applied to the corpuscle, the greater the receptor potential. Once the pressure reaches a critical size (te threshold) an action potential is triggered.

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Related Questions

Which mechanoreceptors detect deep pressure?

Pacinian corpuscle is sensitive to deep pressure.


What layer of skin contains pacinian corpuscles?

The pacinian corpuscle is present in the dermis layer of the skin. Its function is to detect deep pressure and vibration.


What contains mechanoreceptors that detect vibration?

The Pacinian corpuscles contain mechanoreceptors that detect vibration. These receptors are found in the skin, joints, and other connective tissues of the body, and they are sensitive to changes in pressure and vibration. When a vibration is detected, the Pacinian corpuscles generate neural signals that are sent to the brain for processing.


Distinguish among the functions Pacinian corpuscles and Meissner corpuscles?

Pacinian corpuscles are deep in the skin and respond to deep pressure and vibration, while Meissner corpuscles are located closer to the skin surface and are sensitive to light touch and texture. Pacinian corpuscles have a larger receptive field and adapt quickly to stimuli, whereas Meissner corpuscles have a smaller receptive field and adapt slowly.


What genetic disorder comes from pacinian corpuscles?

sickle cell anemia


Is it true that pacinian corpuscles can be exteroceptors interoceptors or proprioceptor?

Yes, pacinian corpuscles are primarily mechanoreceptors responsible for detecting deep pressure and high-frequency vibrations in the skin and joints. Therefore, they are classified as exteroceptors.


What kind of receptors are pacinian corpuscles?

Pacinian corpuscles are mechanoreceptors found in the skin that are sensitive to mechanical pressure and vibration. They are responsible for detecting sensations such as deep pressure and high-frequency vibration.


What is the stimuli for touch?

The stimuli for touch are mechanical pressure, temperature, and vibration on the skin's surface. Specialized receptors in the skin, such as Meissner's corpuscles, Pacinian corpuscles, and Merkel cells, detect these stimuli and send signals to the brain through the nervous system, enabling us to perceive touch sensations.


What are three types of receptors?

There are four different types of receptors in the skin. There are merkel receptors, meissner corpuscles, ruffini cylinders and pacinian corpuscles.


The Golgi tendon organ GTO muscle spindle and Pacinian corpuscles make up the three primary?

Inhibitory proprioceptors


What are sensory receptors that respond to heavy pressure called?

Sensory receptors that respond to heavy pressure are called Pacinian corpuscles.


Does the dermis lack sensory corpuscles and glands?

No, the dermis contains sensory corpuscles such as Meissner's corpuscles and Pacinian corpuscles, which are responsible for detecting sensations like touch and pressure. The dermis also houses glands such as sweat glands and sebaceous glands, which play roles in thermoregulation and skin lubrication.