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A stop codon signals the end of an amino acid chains A STOP codon marks the end of a segment of DNA that is to be transcribed. During transcription, a molecule of messenger RNA (mRNA) is synthesized. The base sequence of this RNA is determined by the base sequence of the template strand of the DNA being transcribed.

When the transcription process reaches a STOP codon, that codon is the last to be transcribed. The mRNA therefore ends with a STOP codon. By convention, the gene is considered to be the base sequence on the non-template strand of DNA, and there are three STOP codons: TAA, TGA, TAG. Any one of these marks the end of the gene.

The corresponding STOP codons in mRNA are: UAA, UGA, UAG.

Mitochondria contain DNA, with 37 genes. In animals, mitochondrial DNA uses TGA (UGA in the mRNA) to code for one of the amino acids, tryptophan, and not as a STOP codon. Plant mitochondria use the "standard" code, with three STOP codons.

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15y ago

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