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Generally, when someone describes lymph nodes as "reactive", they mean that the lymph node abnormality / enlargement is caused by a benign condition (such as an irritant or infection or inflammation) and not a malignancy. It is not always possible to determine to what a node is "reacting", but use of the wording "reactive" generally connotes a benign / non-malignant process.

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Q: What does lymph node reactive changes only mean?
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