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When do kinetochores move toward poles?

Kinetochores move toward the poles during anaphase of mitosis. This movement is driven by the depolymerization of microtubules attached to the kinetochores, pulling the chromosomes to opposite ends of the cell.


Are microtubules polar?

Yes, microtubules are polar structures with distinct plus and minus ends. They grow by adding tubulin subunits predominantly at the plus end, while depolymerization usually occurs more at the minus end. This polarity is essential for microtubule-based processes such as cell division and intracellular transport.


The mitotic spindle formation depends upon?

The formation of the mitotic spindle depends upon the proper assembly and organization of microtubules, which are dynamic protein fibers that make up the spindle apparatus. Microtubules are regulated by microtubule-associated proteins that help facilitate their polymerization and depolymerization processes. Additionally, motor proteins are essential for moving the chromosomes to their correct positions during mitosis.


Mode of Action Of Fenbendazole?

Fenbendazole is a benzimidizole , which inhibits tubulin formation and therefore doesn't allow microtubules to be formed. This disrupts the ability of the parasite to ingest and absorb energy. So basically starves it to death.


Movement of the chromosomes during anaphase would be most affected by a drug that?

inhibits the activity of the motor proteins responsible for pulling the chromosomes to opposite poles of the cell, such as kinesin and dynein.


What is the movement of chromosomes to the center of the cell and later to their respective pole depend upon lengthening and shortening what?

The movement of chromosomes to the center of the cell and later to their respective poles during cell division depends on the lengthening and shortening of spindle fibers, which are composed of microtubules. These fibers attach to the chromosomes at their kinetochores and facilitate their alignment at the metaphase plate and subsequent separation as they pull the chromosomes toward the poles. The dynamic instability of the microtubules, involving cycles of polymerization and depolymerization, drives this movement.


Which checkpoint in the cell cycle is affected by paclitaxel?

Paclitaxel primarily affects the mitotic checkpoint in the cell cycle. It stabilizes microtubules and prevents their depolymerization, disrupting proper spindle formation and leading to mitotic arrest. This interference ultimately triggers cell cycle checkpoints that can result in apoptosis if cells cannot successfully complete mitosis.


What is the stystem of microtubules?

The Cytoskeleton is a system of microtubules, in a cell.


Organelles used to move chromosomes are the?

microtubules


What microtubules are necessary for sorting the chromosomes in cell division?

The kinetochore microtubules


What happens during depolymerization?

Depolymerization is the process of breaking down large polymer molecules into smaller monomer units. This can occur through various methods such as heat, chemical reactions, or enzymes. The resulting monomers can then be used to create new polymers or other products.


What is the reaction called that breaks the monomers apart called?

Decomposition is the process by which molecules are taken apart.