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Movement of the chromosomes during anaphase would be most affected by a drug that?
inhibits the activity of the motor proteins responsible for pulling the chromosomes to opposite poles of the cell, such as kinesin and dynein.
What are spindle fibers composed of?
Spindle fibers are composed of microtubules, which are polymers of the protein tubulin. These microtubules play a crucial role in cell division by helping to separate the chromosomes during mitosis and meiosis.
What structures make up the fibers of the mitotic spindle?
The mitotic spindle is composed of microtubules, which are dynamic structures made up of tubulin protein subunits. It consists of three main types of microtubules: kinetochore microtubules that attach to the chromosomes, polar microtubules that interact with each other to help push the poles of the cell apart, and astral microtubules that anchor the spindle poles to the cell membrane.
Which cytoskeleton fibers are found in cilia and flagella?
Cilia and flagella contain microtubules, which are a type of cytoskeleton fiber made up of tubulin protein subunits. Microtubules provide structural support and are involved in the movement of cilia and flagella.
Is the mitotic spindle primarily composed of microtubules?
Yes, the mitotic spindle is primarily composed of microtubules.
When do kinetochores move toward poles?
Kinetochores move toward the poles during anaphase of mitosis. This movement is driven by the depolymerization of microtubules attached to the kinetochores, pulling the chromosomes to opposite ends of the cell.
Are microtubules polar?
Yes, microtubules are polar structures with distinct plus and minus ends. They grow by adding tubulin subunits predominantly at the plus end, while depolymerization usually occurs more at the minus end. This polarity is essential for microtubule-based processes such as cell division and intracellular transport.
The mitotic spindle formation depends upon?
The formation of the mitotic spindle depends upon the proper assembly and organization of microtubules, which are dynamic protein fibers that make up the spindle apparatus. Microtubules are regulated by microtubule-associated proteins that help facilitate their polymerization and depolymerization processes. Additionally, motor proteins are essential for moving the chromosomes to their correct positions during mitosis.
Mode of Action Of Fenbendazole?
Fenbendazole is a benzimidizole , which inhibits tubulin formation and therefore doesn't allow microtubules to be formed. This disrupts the ability of the parasite to ingest and absorb energy. So basically starves it to death.
Movement of the chromosomes during anaphase would be most affected by a drug that?
inhibits the activity of the motor proteins responsible for pulling the chromosomes to opposite poles of the cell, such as kinesin and dynein.
Which are the most stable of cytoskeletal element?
The most stable of the cytoskeletal elements are microtubules and intermediate filaments. Microtubules provide structural support and are involved in intracellular transport and cell division, while intermediate filaments offer mechanical strength and resilience to cells. Unlike actin filaments, which are more dynamic and involved in cell motility, these elements maintain cell integrity and shape over longer periods. Intermediate filaments, in particular, are known for their durability and resistance to depolymerization.
What is the movement of chromosomes to the center of the cell and later to their respective pole depend upon lengthening and shortening what?
The movement of chromosomes to the center of the cell and later to their respective poles during cell division depends on the lengthening and shortening of spindle fibers, which are composed of microtubules. These fibers attach to the chromosomes at their kinetochores and facilitate their alignment at the metaphase plate and subsequent separation as they pull the chromosomes toward the poles. The dynamic instability of the microtubules, involving cycles of polymerization and depolymerization, drives this movement.
Which checkpoint in the cell cycle is affected by paclitaxel?
Paclitaxel primarily affects the mitotic checkpoint in the cell cycle. It stabilizes microtubules and prevents their depolymerization, disrupting proper spindle formation and leading to mitotic arrest. This interference ultimately triggers cell cycle checkpoints that can result in apoptosis if cells cannot successfully complete mitosis.
Why taxol has no effect on bacterial cells?
Taxol, or paclitaxel, is a chemotherapy drug that stabilizes microtubules and inhibits cell division in eukaryotic cells, particularly cancer cells. Bacterial cells, however, lack microtubules and the cytoskeletal structures that Taxol targets, rendering the drug ineffective against them. Additionally, bacterial cell division relies on different mechanisms, such as binary fission, which are unaffected by Taxol's action on eukaryotic microtubules. As a result, Taxol does not have any significant impact on bacterial growth or division.
What is the stystem of microtubules?
The Cytoskeleton is a system of microtubules, in a cell.
Organelles used to move chromosomes are the?
microtubules
What microtubules are necessary for sorting the chromosomes in cell division?
The kinetochore microtubules
