GTP
inhibits the activity of the motor proteins responsible for pulling the chromosomes to opposite poles of the cell, such as kinesin and dynein.
Spindle fibers are composed of microtubules, which are polymers of the protein tubulin. These microtubules play a crucial role in cell division by helping to separate the chromosomes during mitosis and meiosis.
The mitotic spindle is composed of microtubules, which are dynamic structures made up of tubulin protein subunits. It consists of three main types of microtubules: kinetochore microtubules that attach to the chromosomes, polar microtubules that interact with each other to help push the poles of the cell apart, and astral microtubules that anchor the spindle poles to the cell membrane.
Cilia and flagella contain microtubules, which are a type of cytoskeleton fiber made up of tubulin protein subunits. Microtubules provide structural support and are involved in the movement of cilia and flagella.
Yes, the mitotic spindle is primarily composed of microtubules.
Kinetochores move toward the poles during anaphase of mitosis. This movement is driven by the depolymerization of microtubules attached to the kinetochores, pulling the chromosomes to opposite ends of the cell.
Yes, microtubules are polar structures with distinct plus and minus ends. They grow by adding tubulin subunits predominantly at the plus end, while depolymerization usually occurs more at the minus end. This polarity is essential for microtubule-based processes such as cell division and intracellular transport.
The formation of the mitotic spindle depends upon the proper assembly and organization of microtubules, which are dynamic protein fibers that make up the spindle apparatus. Microtubules are regulated by microtubule-associated proteins that help facilitate their polymerization and depolymerization processes. Additionally, motor proteins are essential for moving the chromosomes to their correct positions during mitosis.
Fenbendazole is a benzimidizole , which inhibits tubulin formation and therefore doesn't allow microtubules to be formed. This disrupts the ability of the parasite to ingest and absorb energy. So basically starves it to death.
inhibits the activity of the motor proteins responsible for pulling the chromosomes to opposite poles of the cell, such as kinesin and dynein.
The movement of chromosomes to the center of the cell and later to their respective poles during cell division depends on the lengthening and shortening of spindle fibers, which are composed of microtubules. These fibers attach to the chromosomes at their kinetochores and facilitate their alignment at the metaphase plate and subsequent separation as they pull the chromosomes toward the poles. The dynamic instability of the microtubules, involving cycles of polymerization and depolymerization, drives this movement.
Paclitaxel primarily affects the mitotic checkpoint in the cell cycle. It stabilizes microtubules and prevents their depolymerization, disrupting proper spindle formation and leading to mitotic arrest. This interference ultimately triggers cell cycle checkpoints that can result in apoptosis if cells cannot successfully complete mitosis.
The Cytoskeleton is a system of microtubules, in a cell.
microtubules
The kinetochore microtubules
Depolymerization is the process of breaking down large polymer molecules into smaller monomer units. This can occur through various methods such as heat, chemical reactions, or enzymes. The resulting monomers can then be used to create new polymers or other products.
Decomposition is the process by which molecules are taken apart.