ADH is know as vassopressin and is produces by the hypothalamus and stored in the posterior pituitary. It is a peptide neurohormone of about 9 amino acids in length. ADH stands for anti diuretic hormone and prevents excess urine formation by reabsorbing water. When osmoteceptor cells in the hypothalamus senses an increase in osmolaritg in the ECF, SON and PVN cells are stimulated to secrete ADH. Also baroreceptors in the large arteries sense decreases in blood pressure and blood volume due to fluid loss. This also stimulus ADH secretion in order to conserve water. Interestingly, alcohol inhibits ADH secretion, therefore producing very dilute urine which stimulates thirst.
releasing factors from the hypothalamus
The ADH feedback loop is an example of a negative feedback loop. Negative feedback loops occur when the output of a system acts to oppose the changes to the input of the system. This is the case with ADH because when there is not enough water, the hypothalamus and pituitary gland work to release ADH so that the body can retain more water.
ADH is short for Anti Diuretic Hormone and it prevents excess water loss. As such, a hyper-secretion of ADH will result in less urine by volume, and the urine will have a lower concentration of water. Conversely, it will have a higher concentration of solutes (Sodium, Potassium, Urea, etc.)
ADH (Antidiuretic Hormone)
Antidiuretic hormone (ADH): A relatively small (peptide) molecule that is released by the pituitary gland at the base of the brain after being made nearby (in the hypothalamus). ADH has an antidiuretic action that prevents the production of dilute urine (and so is antidiuretic). ADH is also known as vasopressin.As with most processes in the body, it works in what is called a negative feedback situation.This feedback system reduces the output of a system. (In physiology) a decrease in function in response to a stimulus. For example, the secretion of follicle-stimulating hormone decreases as the amount of circulating estrogen increases.
ADH secretion is stimulated by increase in plasma osmolarity. Example:ingestion of Na+ will cause the plasma osmolarity to increase and trigger the pituitary gland to produce ADH.
The ADH feedback loop is an example of a negative feedback loop. Negative feedback loops occur when the output of a system acts to oppose the changes to the input of the system. This is the case with ADH because when there is not enough water, the hypothalamus and pituitary gland work to release ADH so that the body can retain more water.
The ADH feedback loop is an example of a negative feedback loop. Negative feedback loops occur when the output of a system acts to oppose the changes to the input of the system. This is the case with ADH because when there is not enough water, the hypothalamus and pituitary gland work to release ADH so that the body can retain more water.
antidiuretic hormone(ADH)
increased plasma osmolality
Diabetes insipidus
ADH secretion and oxytocim release
Diabetes insipidus
diabetes insipidus
ADH is short for Anti Diuretic Hormone and it prevents excess water loss. As such, a hyper-secretion of ADH will result in less urine by volume, and the urine will have a lower concentration of water. Conversely, it will have a higher concentration of solutes (Sodium, Potassium, Urea, etc.)
ADH (Antidiuretic Hormone)
the puturitary gland releases 65% more urine than it would normally if the ADH hormone had been stabilised
Alcohol (ethanol) acts on the hypothalamus to inhibit ADH secretion. This leads to diuresis and the typical repeated trips to the bathroom while at the bar drinking.