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What is Glycagon?

Updated: 4/28/2022
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14y ago

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Glycagon is a 29 amino acid polypeptide and is an extremely potent hyperglycemic agent. It's a hormone that is produced from alpha cells in the pancreas. Its target is the liver, where it promotes the: 1) break down of glycogen to glucose 2) synthesis of glucose from lactic acid and from noncarbohydrate molecules 3) release of glucose into the blood by liver cells, raising blood glucose levels

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Q: What is Glycagon?
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How does the body work and regulate insulin and glycagon?

The body regulates insulin by either not making it in the pancreas or making it. It filters Glycogen (glucose) by either filtering your blood in the liver and removing it if there is too much or making it. You get it from eating sugar. Hope this helps =)


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Firstly, glycogen is a polysaccharide of glucose (made up from lots of glucose monomers), and functions as the primary short term energy storage in animal cells (mostly in liver). When the organism needs energy, it sends a signal (hormones: adrenaline and glucagon) to the cells of the liver, so that they would start decomposing glycogen (separating it into its smaller parts - glucose). Then glucose is secreted (thrown out) into the blood, so that other cells can use it to do work. If you need a more scientific explanation: When a signal molecule of adrenaline or glucagon attaches to the receptor of the glycagon containing cell, the receptor activates adenylyl cyclase (transmembrane protein), which converts ATP to cAMP (cyclic adenine monophosphate). cAMP activates protein kinase A (PKA), which activates phosphorilase kinase b, which then activates glycogen phosphorilase. Only then glycogen phosphorilase catalyses the reaction of glycogen decomposure into glucose.


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What is stored?

Firstly, glycogen is a polysaccharide of glucose (made up from lots of glucose monomers), and functions as the primary short term energy storage in animal cells (mostly in liver). When the organism needs energy, it sends a signal (hormones: adrenaline and glucagon) to the cells of the liver, so that they would start decomposing glycogen (separating it into its smaller parts - glucose). Then glucose is secreted (thrown out) into the blood, so that other cells can use it to do work. If you need a more scientific explanation: When a signal molecule of adrenaline or glucagon attaches to the receptor of the glycagon containing cell, the receptor activates adenylyl cyclase (transmembrane protein), which converts ATP to cAMP (cyclic adenine monophosphate). cAMP activates protein kinase A (PKA), which activates phosphorilase kinase b, which then activates glycogen phosphorilase. Only then glycogen phosphorilase catalyses the reaction of glycogen decomposure into glucose.


How do the liver and pancreas help digest food?

The liver secretes bile which aids in the breakdown of lipids into fatty acids. The enzymes which speeds up the rate of the digestion of lipids is Lipase, and this is secreted by the pancreas. The pancreas also secretes many other enzymes including: Two protease's are trypsin and chymotrypsin. These enzymes speed up the rate in which protein is digested into amino acids. Amylase is also produced in the pancreas (As well as the salivary glands in the mouth), and amylase breaks down starch into maltose molecules