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Robert koch showed that diseases can be transmitted by blood. he innoculated healthy mice with blood from a diseased mice and shows that the healthy mice became infected, with the causitive agent being the same microbe.

he provided the proof that was needed to convince people that microscopic pathogens cause disease. His first experiments were with the disease anthrax in sheep. Later, he obtained similar results for tuberculosis and cholera.

he developed new ways of isolating strains of bacteria

Koch was able to state a series of steps that are needed to identify the micro-organism responsible for a particular disease. These steps are called Koch's postulates.

    • Step 1: All infected hosts must contain the suspect organism.
    • Step 2: A pure culture of the suspect organism must be obtained.
    • Step 3: A healthy organism infected with the pure culture must have the same symptoms as the original host.
    • Step 4: The suspect organism must be isolated from the second host, grown in pure culture and prove to be identical to the first culture.
  • Koch's postulates can be used to identify the causative organism of an infectious disease. The symptoms of the disease are carefully identified and then the blood of sufferers is examined to determine possible causative organisms.
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