What is the difference between pai-1 5g4g heterozygous and pai-1 4g4g homozygous?

Answer 1

PAI-1 heterozygous is an inherited blood disorder from ONE parent-ONE copy of the gene. PAI-1 Homozygous is an inherited blood disorder from BOTH parents-TWO copies of the gene.

Answer 2

In PAI-1 5G4G heterozygous, one allele carries the 5G variant and the other allele carries the 4G variant of the gene. In PAI-1 4G4G homozygous, both alleles carry the 4G variant. This genetic difference can impact the regulation of PAI-1 activity, affecting factors like blood clotting and cardiovascular disease risk.