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The two strands in a DNA molecule (the polynucleotides) are complementary to each other. This means that the base sequence in one strand determines the base sequence in the other strand. This happens because of specific base pairing. An adenine in one strand always pairs with a thymine in the other strand, and a cytosine in one strand always pairs with a guanine in the other strand. So if you know the base sequence in one strand of the DNA yoiu can work out the sequence in the complementary strand. See: http://www.phschool.com/science/biology_place/biocoach/dnarep/basepair.html
DNA strands run anti-parallel from one another, and have a double helix structure. The strands are held together by hydrogen bonds between base pairs that are weak individually, but collectively strong.

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