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These are the steps in bone development which begins in the second month of development:

â—¾Uses hyaline cartilage "bones" as models for bone construction
â—¾Requires breakdown of hyaline cartilage prior to ossification
Stages of Endochondral Ossification
â—¾Formation of bone collar
â—¾Cavitation of the hyaline cartilage
â—¾Invasion of internal cavities by the periosteal bud, and spongy bone formation
â—¾Formation of the medullary cavity; appearance of secondary ossification centers in the epiphyses
â—¾Ossification of the epiphyses, with hyaline cartilage remaining only in the epiphyseal plates

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