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Golgi apparatus

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Q: What organelles possesses a cis and trans side composed of cisternae?
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What are cisternae in Golgi apparatus?

# A cisterna (plural cisternae) comprises a flattened membrane disk that makes up theGolgi apparatus. A typical Golgi has anywhere from 3 to 7 cisternae stacked upon each other like a stack of dinner plates, but there are usually around 6. The cisternae carry Golgi enzymes to help or to modify cargo proteins traveling through them destined for other parts of the cell. # The cisternae also carry structural proteins important for its maintenance as a flattened membrane and its stacking upon each other. # The earliest cisternae are called the cis-cisternae, followed by the medial cisternae, then the trans-cisternae (as they move away from the endoplasmic reticulum). # The formation of new cisternae is often called the cis-Golgi network and at the end of the Golgi where transport to other parts of the cell occurs is called the trans-Golgi network. Both are thought to be specialized cisternae leading in and out of the Golgi apparatus. # Cisternae may also refer to flattened regions of the rough endoplasmic reticulum.


What are the steps of the secretory pathway?

Protein SynthesisEndoplasmic Reticulum-->cis Golgi cisternae --> medial Golgi cisternae --> trans Golgi Cisternae --> Plasma membraneExtra Cellular SpaceAs they are being synthesized, secretory proteins enter the lumen of the endoplasmic reticulum. From the ER, vesicles transport these proteins to the Golgi, where they are sequentially modified and concentrated in a cis-to-trans direction. Secretory vesicles bud from the Golgi and move along cytoskeletal filaments to eventually fuse with the plasma membrane, secreting their protein cargo. Each of these transport steps requires specialized proteins to ensure that the cargo is sent to the proper location and is able to fuse with the target membrane.


Where does cisternal maturation occur?

Cisternal maturation occurs in the Golgi apparatus. This is where the cisternae move, beginning at the cis face and progressing via the medial face to the trans face.


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