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Nucleosomes are the basic repeating units of chromatin which is a combination of DNA and proteins that make up the content's of a cell's nucleus. Nucleosomes are made of a histone octamer which is comprised of two of the following histones: H2A, H2B, H3, and H4. The histone octamer is bound and wrapped around approximately 146 base pairs of DNA and an additional H1 histone is added and is wrapped around 20 more base pairs.

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9y ago
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9y ago

Nucleosomes are the basic unit of DNA packaging in eukaryotes. They are made of a segment of DNA wound around a histone protein core, a structure often compared to thread wrapped around a spool.

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11y ago

The nucleosome is the basic repeating subunit of chromatin. It consists of a nucleosome core particle of 146-147 base pairs of DNA wound 1.67 times around a histone octomer. It has been compared to thread wrapped around a spool. If histone H1 is added to the core particle, you then have a chromatosome. Chromatosomes are connected by stretches of linker DNA that vary in size up to about 80 bp and produces the appearance of beads on a string. The term nucleosome is commonly used in reference to the nucleosome core particle but technically it is the chromatosome plus one stretch of linker of DNA; it forms a repeating unit of DNA of about 200 bp.

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10y ago

Nucleosomes form the fundamental repeating units of eukaryotic chromatin

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10y ago

Nucleosomes are made of the organic substance known as protein. There are a total of eight different proteins that make up one nucleosomes, which are also composed of DNA.

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12y ago

DNA wrapped around histone proteins

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Q: What organic substance is a nucleosome composed of?
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What is a nucleosome and what organic component is it primarily composed of?

Chromatin composed of tetramer of histones 2 copies each of Histone H2A, H2B, H3 and H4. DNA is bound on the nucleosome and uses 147 basepairs of DNA.


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