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Detergent effects the phosopholipid bi-layer. Because it is lipophilic, it emulsifies the bi-layer, causing it to form miscelles. As a result, it is disrupted, and therefore anything inside of the cell can leak out. (eg. betacynin in beetroot cells)

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What effect does a detergent have on the integrity of cells if a lipid is added to the detergent?

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