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Histones function in the packaging of DNA as well as in regulation of gene expression in eukaryotic (and some bacterial) cells. Histone proteins are among the most highly conserved proteins in eukaryotes, emphasizing their requirement for the survival of more complex life forms. Cells deficient in histones likely would not survive as the complex genomes of eukaryotes would not have the necessary levels of regulation as well as the DNA would not be efficiently packed and would be fragile and highly susceptible to damage.

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Why might chromatin be tangled in the nucleus?

Chromatin can become tangled in the nucleus due to the complex folding and packaging of DNA around histone proteins. Additionally, during processes like DNA replication, transcription, or repair, chromatin can become more dynamic and may become tangled temporarily as proteins interact with it to carry out these functions.


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What are 3 sources from which a hypothesis may arise?

Invariably, they arise out of a curious mind. People make observations and notice what might be subtle patterns in the information, or they think about a problem in one field by playing with ideas from another field, or a thought comes after struggling with a problem for a long time. They can arise in any number of ways; but they all have curious minds as their means of expression.


What might happen if apoptosis did not occur in cells that have significant DNA damage?

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What is a iatrogenic disease?

Iatrogenic disease refers to a condition or disorder that is inadvertently caused by medical treatment or procedures. This can include medication side effects, complications from surgery, or infections acquired in healthcare settings.

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