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It would collapse into a shapeless bag that would not be able to do the work of a cell.

One for instance.

As you may, or may not know, the cell uses vesicles to transport material around the cell and out of the cell. Without the microtubules ( cytoskeleton " girders " ) motor proteins, Kinesins, would have no where to walk the vesicles to their destinations. This does not even take into consideration the three classes of cytoskeleton and their various structural and signally functions in the cell.

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