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Macro anatomy of liver

For the ease of understanding , liver is anatomically divided into lobes. On its top view, liver shows the left and right lobes separated by the falciform ligament. On the inferior view (from below), it appears with four lobes. However, the organ is roughly divided into 2 principal lobes, right and a left lobe. The falciform ligament forms a septum resulting in the left and right lobes. The abdomen and the liver is thinly separated by a membrane called peritoneum. Peritoneum is the covering layer of all the abdominal organs. Peritoneum has 2 divisions; outer parietal divisions and the inner visceral layer that actually touches the surface of liver. Liver is surrounded by a number of organs forming various impressions. Some of the impressions are gastric impression, renal impression, suprarenal impression, colic impression, and duodenal impression.

Microscopic anatomy of liver

Unlike other organs, the liver is supplied with two major sources of blood; the portal channel and the hepatic channel. The hepatic artery connected to the major abdominal aorta brings pure blood from the heart, similarly, the impure blood is removed from the liver with the help of 3 hepatic veins. Additionally, portal circulation rich in multiple capillaries and veins also supply the blood from in and out of the liver. Microscopically, liver is divided into a number of hepatic lobules. Each lobule appears hexagonal made up of plates of hepatocytes. Hepatocytes (liver cells) joins the central vein that carry blood out of the liver. If we analyse the histology (microscopic anatomy) of the liver, two major types of liver cells are found: parenchymal cells and the non-parenchymal cells. 3/4th of the liver is filled with the parenchymal hepatocytes and the remaining ¼ is made up of non-parenchymal cells. The liver contains sinusoids, lined with 2 types of cells called sinusoidal endothelial cells, and phagocytic Kupffer cells. Furthermore, hepatic stellate cells are one of the type of non-parenchymal cells found alongside perisinusoidal space, between a sinusoid and a hepatocyte, some intrahepatic lymphocytes are often found within the sinusoidal lumen. The functional lobes of the liver are separated by the imaginary plane called Cantlie's line that joins the gallbladder fossa to the inferior vena cava. The plane separates the liver into left and the right lobes. The middle hepatic vein also demarcates the true right and left lobes.

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Related Questions

What organelle is abundant in liver cells?

ER


Is liver apart of lympathetic system?

Yes, natural killer cells and natural killer T cells, are very abundant in the liver.


Which structure is primarily involved in the detoxification process and therefore abundant in liver cells?

The smooth endoplasmic reticulum are involved in detoxification. They are a part of every sort of cell, but are particularly useful in liver cells.


Is smooth ER or rough ER abundant in liver cells?

The smooth endoplasmic reticulum (SER) is more abundant in liver cells compared to the rough endoplasmic reticulum (RER). This is because the liver is involved in lipid metabolism and detoxification processes, which require the functions of the SER such as lipid synthesis and drug metabolism.


What are the most abundant in cells?

the most abundant chemical in cells is water.


What kind of organelle would you expect to find very abundant in liver cells that are engaged in detoxifying lipid-soluble drugs?

The kind of organelle that is very abundant in liver cells is the endoplasmic reticulum (ER), specifically the smooth ER. It is found in the hepatocytes of the liver that detoxifies lipid-soluble drugs.


The functional unit of the liver is known as?

the hepatic lobule is the structural and functional unit of the liver. there are about 50,000 - 1,00,000 lobules in the liver. the lobule is a honey comb like structure and it is made up of liver cells called hepatocytes.


What organs is endoplasmic reticulum most abundant?

Organs that would contain a lot of er including smooth e.r. would be the liver and the kidneys places where detoxification of anything thats not a proper substrate or foreign substances I.E. alcohol, drugs, chemicals and so on. Keeping the body clean and free of harmful substances.


Is the liver composed of the body cells?

no. a kidney is not composed of body cells. but liver, sperm, and a single bone are composed of body cells. :)


What are the cells that make up the liver?

there are penitential cells in the liver, -narb


Which process occurs when new liver cells are produced from old liver cells?

The process is called liver regeneration, where old liver cells divide to produce new liver cells. This helps in repairing damaged tissue and maintaining normal liver function.


What elments are abundant in blood?

Red blood cells are the most abundant White blood cells are the second most Platelets are the least abundant