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Cystic fibrosis is an autosomal recessive disease. That means that each parent has to carry a mutation and will have a 1 in 4 (25%) chance of having a child with CF. The previous answer is not correct.

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You inherit cystic fibrosis from either one parent or both. It is to do with genetic mapping. Cystic fibrosis is a recessive gene and can be carried by our parents even if they do not suffer from it, it's like in a carrier(someone who does not suffer from CF but still has the gene) the cystic fibrosis gene is 'hiding'. When we crete gametes (sperm and eggs) the genes have to split. For example your father could have the gene Ff and they would split and become F f. The capital F is the dominant gene and the small f is the recessive gene, in this case cystic fibrosis. When an egg is fertilised the separate gene from both parents join together. If a man and women have one child, and both parents had the recessive gene of CF then the likelihood of their first child having cystic fibrosis is high, 50% in fact. Here is a diagram which might help explain

Parents Mother + Father

Genotype (genes) Ff Ff

Gametes(sperm+egg) F f F f

Offspring FF ff

50% 50%

I hope this helped a little. I didn't go into full detail becasue there is a lot more to it then what i have said and it is a lot more comlicated. If you can, try to go on a revision site which may help.

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