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A molecules ability to travel across a cell membrane depends on, among other things;

1. The concentration of the molecule inside and outside of the cell (molecules may travel against the concentration gradient using protein pumps at the cost of ATP).

2. The size of the molecule (large molecules are less likely to pass).

3. The polarity of the molecule (charged molecules have a more difficult time crossing the cell membrane).

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10y ago
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13y ago

1) If it is too big, then it may not go pass the cell membrane.

2) H20 CAN NOT cross! For example, for is is hydrophobic.

The phospholipid bilayer determines what goes pass the cell membrane.

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11y ago

The main one is Size; next is [molecular] polarity or lack thereof - polar substances have charges [hydrophylls] while non-polar substances do not [hydrophobes].

While the above is true it is complicated by the fact that the Cell membrane has both an interior and an exterior hydrophyllic face, as well as a hydrophobic interior 'space'.

Transmembrane proteins typically have polar sections/segments that locate outside of the membrane while the non-polar segments reside in the hydrophobic 'center' of the membrane.

These transmembrane proteins typically form the Gates that selectively allow passage into the Cell of all forms of Substances.

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15y ago

electrical charge, size, hydrophilic/phobic

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13y ago
Their size
Their charge
and if they are hydrophilic or phobic
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9y ago

There are many factors that can influence the diffusion process of a molecule crossing a membrane. The three main factors are concentration, temperature and surface area.

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13y ago

It depends if it has an electrical charge, how big it is, and if it is hydrophilic/phobic.

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Q: What three factors will determine whether a molecule will diffuse into a cell?
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