0
Where can you find the genomic and transcript sequences of the gene PKD1 and the amino acid sequence of the protein polycystin-1?
Try the NCBI (National Center for Biotechnology Information) site. On the home page (there is a link below) enter PKD1 in the search box.
A good website for human (and other) gene locations and sequences is Ensembl. Try, for example, clicking the link below, and use the left side-bar, or scroll down for the transcript sequence.
All information on the Ensembl website is in the public domain.
There is relevant discussion in Cell 1995 Apr 21; 81(2):289-9. See the Cell Press link below for a PDF of the Cell article.
What else can I help you with?
What is the difference between RefSeq and GenBank?
RefSeq is a curated database of reference sequences that includes genomic, transcript, and protein sequences, while GenBank is a comprehensive database that stores raw DNA and RNA sequences submitted by researchers. RefSeq focuses on high-quality sequences that represent well-studied genes, while GenBank houses a wider range of genetic data, including draft sequences and sequences from ongoing research projects.
What is genomic data?
Genomic data refers to information about an organism's complete set of DNA, including its genes and other sequences. This data can be used to study genetic variations, traits, and diseases, and to understand how genes work together to control biological processes. Advances in sequencing technologies have made it easier and more affordable to generate large amounts of genomic data for research and clinical applications.
What phenomenon occurs when a particular alelle will either be expressed or silenced depending on whether it is inherited from a male or female?
Genomic imprinting is the phenomenon where a particular allele is expressed or silenced depending on whether it is inherited from the mother or the father. This process is regulated by epigenetic mechanisms such as DNA methylation that affect gene expression without altering the underlying DNA sequence.
Can clones isolated from cDNA libraries contain promoter sequences?
No, clones isolated from cDNA libraries do not contain promoter sequences because the cDNA synthesis process does not retain regulatory elements such as promoters. cDNA is made from mature mRNA and lacks the non-coding regions found in genomic DNA, including promoters. Therefore, clones isolated from cDNA libraries do not include promoter sequences.
What is the difference between genomic and bioinformatics?
genomics is the study of an entire sequence of an organism's DNA, while bioinformatics is the use of computers and data bases to organize and analyze DNA. bioinformatics makes genomics a bit easier.
What is the difference between RefSeq and GenBank?
RefSeq is a curated database of reference sequences that includes genomic, transcript, and protein sequences, while GenBank is a comprehensive database that stores raw DNA and RNA sequences submitted by researchers. RefSeq focuses on high-quality sequences that represent well-studied genes, while GenBank houses a wider range of genetic data, including draft sequences and sequences from ongoing research projects.
Does a restriction enzyme generate the same size fragments in genomic DNA of different species?
No, restriction enzymes do not always generate the same size fragments in genomic DNA of different species. The specific DNA sequences recognized by the enzyme and the distribution of those sequences in the genome will determine the size and distribution of the fragments produced. Differences in genome size, organization, and sequence between species will result in variation in fragment sizes.
What is a genomic library?
Specific human genes stored in virus, bacteria and yeast hosts no, the genes are randomly inserted into vectors. a cDNA library houses tissue-specific sequences derived from an mRNA transcript so that it contains only genes that code for protein.
What is endogenous promoters?
Endogenous promoters are DNA sequences located upstream of a gene that initiate and regulate the transcription of that gene. These promoters are part of the gene's natural genomic sequence and play a crucial role in controlling gene expression in living organisms.
Are blue eyes a mutation?
No. Mutations are changes in a genomic sequence. Blue eyes are not changes.
What is the first gene name in gene sequence?
The first gene name in a gene sequence typically refers to the first gene identified or annotated within a specific genomic context. However, without specific context or a reference genome, it is impossible to determine an exact gene name, as gene sequences vary widely across different organisms and individual genomes. In general, gene names often follow conventions based on the organism, function, or other characteristics, such as "TP53" for the tumor protein p53 gene in humans. To identify the first gene in a particular sequence, one would need to analyze that specific genomic data.
What is genomic region?
A genomic region refers to a specific part of a genome that may contain one or more genes along with regulatory elements. It can vary in size and is typically defined by its unique DNA sequence. Researchers often study genomic regions to understand their functions and the genetic variations present within them.
What types of DNA sequencing in their DNA?
The types of DNA sequencing are whole-genome sequencing which maps entire DNA sequences, targeted sequencing which focuses on specific genomic regions, and RNA sequencing which identifies gene expression levels.
What is genomic data?
Genomic data refers to information about an organism's complete set of DNA, including its genes and other sequences. This data can be used to study genetic variations, traits, and diseases, and to understand how genes work together to control biological processes. Advances in sequencing technologies have made it easier and more affordable to generate large amounts of genomic data for research and clinical applications.
What is the complete collection of cloned DNA fragments from one organism?
A genomic library is the complete collection of cloned DNA fragments from one organism. These fragments are typically inserted into vectors and stored in a host organism, allowing researchers to study and analyze specific genes or sequences.
What did Haseltine begin patenting?
human genomic sequences that had the potential for medical use. He formed partnerships with major pharmaceutical companies and garnered a reputation for giving brilliant presentations to venture capitalists.
What is a genomic location?
A genomic location refers to a specific position or region on a chromosome where a particular gene, DNA sequence, or genetic marker is found. It is typically described using coordinate systems, such as base pair positions, which indicate the precise spot on the DNA strand. Understanding genomic locations is crucial for studying gene function, genetic variations, and their associations with diseases.
