Which cells secrete insulin?

Answer 1

<liver cells, muscles cells but not nerve cells>

You have to remember that under regular conditions the production of ATP is derived from glucose. Every cell needs ATP to function for that reason all cells in the body need glucose to function under regular conditions. Since insulin is the hormone that signals cells to take up glucose and glucose is needed to efficiently produce ATP it makes sense that virtually every cell in the body responds to insulin including nerve cells.

Answer 2

Insulin is secreted by beta cells in the pancreas, specifically in the islets of Langerhans. These beta cells are located in clusters within the pancreas and are responsible for producing and releasing insulin in response to changes in blood glucose levels.

Answer 3

Insulin is produced in the pancreas and released when any of the several stimuli is detected. The stimuli include ingested protein and glucose in the blood produced from digested food. Carbohydrate can be polymers of simple sugars or the simple sugars themselves. If the carbohydrate includes glucose then that glucose will be absorbed into the blood stream and blood glucose level will begin to rise. In target cells, insulin initiates a signal transduction, which has the effect of increasing glucose uptake and storage. Finally, insulin is degraded, terminating the response.Insulin undergoes extensive posttranslational modification along the production pathway. Production and secretion are largely independent; prepared insulin is stored awaiting secretion. Both C-peptide and mature insulin are biologically active. Cell components and proteins in this image are not to scale.

In mammals, insulin is synthesized in the pancreas within the beta cells (β-cells) of the islets of Langerhans. One million to three million islets of Langerhans (pancreatic islets) form the endocrine part of the pancreas, which is primarily an exocrine gland. The endocrine portion only accounts for 2% of the total mass of the pancreas. Within the islets of Langerhans, beta cells constitute 60-80% of all the cells.

In beta cells, insulin is synthesized from the proinsulin precursor molecule by the action of proteolytic enzymes, known as prohormone convertases (PC1 and PC2), as well as the exoprotease carboxypeptidase E. These modifications of proinsulin remove the center portion of the molecule (ie, C-peptide), from the C- and N- terminal ends of proinsulin. The remaining polypeptides (51 amino acids in total), the B- and A- chains, are bound together by disulfide bonds/disulphide bonds. Confusingly, the primary sequence of proinsulin goes in the order "B-C-A", since B and A chains were identified on the basis of mass, and the C peptide was discovered after the others.

Answer 4

beta cells in islet of Langerhans (pancreas)

Answer 5

They're responsible for most of the insulin-stimulated uptake of plasma glucose.

Answer 6

Actually, insulin is produced by Beta cells which are essentially produced and located in Islet of Langerham ( in the endocrine pancreas)

Answer 7

Liver cells, as well as most other cells in the body.

Answer 8

They are liver cells. Some muscle cells can be affected

Answer 9

Mainly cells of liver. Also many muscle cells too,

Answer 10

Beta cells