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Which cells secrete insulin?

Updated: 6/10/2024
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Wiki User

14y ago

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<liver cells, muscles cells but not nerve cells>

You have to remember that under regular conditions the production of ATP is derived from glucose. Every cell needs ATP to function for that reason all cells in the body need glucose to function under regular conditions. Since insulin is the hormone that signals cells to take up glucose and glucose is needed to efficiently produce ATP it makes sense that virtually every cell in the body responds to insulin including nerve cells.

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12y ago
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1mo ago

Insulin is secreted by beta cells in the pancreas, specifically in the islets of Langerhans. These beta cells are located in clusters within the pancreas and are responsible for producing and releasing insulin in response to changes in blood glucose levels.

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14y ago

Insulin is produced in the pancreas and released when any of the several stimuli is detected. The stimuli include ingested protein and glucose in the blood produced from digested food. Carbohydrate can be polymers of simple sugars or the simple sugars themselves. If the carbohydrate includes glucose then that glucose will be absorbed into the blood stream and blood glucose level will begin to rise. In target cells, insulin initiates a signal transduction, which has the effect of increasing glucose uptake and storage. Finally, insulin is degraded, terminating the response.Insulin undergoes extensive posttranslational modification along the production pathway. Production and secretion are largely independent; prepared insulin is stored awaiting secretion. Both C-peptide and mature insulin are biologically active. Cell components and proteins in this image are not to scale.

In mammals, insulin is synthesized in the pancreas within the beta cells (β-cells) of the islets of Langerhans. One million to three million islets of Langerhans (pancreatic islets) form the endocrine part of the pancreas, which is primarily an exocrine gland. The endocrine portion only accounts for 2% of the total mass of the pancreas. Within the islets of Langerhans, beta cells constitute 60-80% of all the cells.

In beta cells, insulin is synthesized from the proinsulin precursor molecule by the action of proteolytic enzymes, known as prohormone convertases (PC1 and PC2), as well as the exoprotease carboxypeptidase E. These modifications of proinsulin remove the center portion of the molecule (ie, C-peptide), from the C- and N- terminal ends of proinsulin. The remaining polypeptides (51 amino acids in total), the B- and A- chains, are bound together by disulfide bonds/disulphide bonds. Confusingly, the primary sequence of proinsulin goes in the order "B-C-A", since B and A chains were identified on the basis of mass, and the C peptide was discovered after the others.

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14y ago

beta cells in islet of Langerhans (pancreas)

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13y ago

They're responsible for most of the insulin-stimulated uptake of plasma glucose.

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13y ago

Actually, insulin is produced by Beta cells which are essentially produced and located in Islet of Langerham ( in the endocrine pancreas)

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11y ago

Liver cells, as well as most other cells in the body.

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8y ago

They are liver cells. Some muscle cells can be affected

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8y ago

Mainly cells of liver. Also many muscle cells too,

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13y ago

Beta cells

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Q: Which cells secrete insulin?
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Related questions

Beta cells which constitute 80 percent of the pancreases hormone producing cells secrete?

Beta cells secrete insulin, alpha cells secrete glucagon.


What do alpha cells secrete?

alpha cells just like beta and gamma cells secrete radiation. These were discovered by a french scientist in the 1800's


What does the pancreas release?

The pancreas is endocrine (producing several important hormones, including insulin, glucagon, and somatostatin). The most important is insulin which controls the take-up of glucose by the body's cells.


What hormone does beta cells secrete and why?

Beta cells secrete insulin, which helps to regulate blood sugar levels by facilitating the uptake of glucose from the bloodstream into cells. Insulin also plays a key role in storing excess glucose as glycogen in the liver and muscles for later use.


What glands secrete hormones such as insulin?

The beta cells of the Isles of Langerhaans in the pancreas secrete insulin.


Which pancreatic cells secrete insulin?

Insulin is secreted by beta cells, which are a type of pancreatic islet cell located in the islets of Langerhans within the pancreas. Beta cells play a key role in regulating blood sugar levels by releasing insulin in response to high glucose levels in the blood.


Specialized islet cells that secrete hormones are found scattered throughout the?

Specialized islet cells that secrete hormones are found scattered throughout the Pancreas.


The islet cells of the pancreas secrete?

insulin and Glucagon - both are hormones which control glucose levels in the blood.


What cells in the pancreas that secrete glucagon are called?

The cells in the pancreas that secrete glucagon are called alpha cells. These cells are located in the islets of Langerhans within the pancreas and are responsible for producing and releasing glucagon in response to low blood sugar levels.


Why is insulin not made in any other body cells?

Insulin is primarily produced in the pancreas by specialized cells called beta cells. These cells are uniquely equipped to synthesize and secrete insulin in response to changes in blood glucose levels. Other body cells do not have the necessary enzymes and machinery to produce insulin.


What is the name of the organ containing the glands that secrete insulin and glucagon?

Beta cells of the pancreas produce insulin.


What part of the endocrine system secretes insulin?

good question! actually Pancreas is the gland that produces insulin. Inside the Pancreas are tiny cells called beta cells which form groups. The groups are called "Islets of Langerhans" which secrete insulin directly into the blood stream.