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In humans, the bone marrow - that virtual space within larger bones of the skeletal system - primarily serves as non-distensible, temperature, and hemodynamically-stable 'nursery' for the hematopoetic (RBC-red blood cells) and megakaryocytic(platelets) cell lines. While other fully-maturated cells of the monocytic, lymphocytic, and neutrophylic (immune system) - are often found there, too, they are typically observed as fully mature cells going about their purposeful migrations as they easily slip through membranes, exploring and ridding the body for foreign invaders, such as parasites, viruses, bacteria, fungi, and debris. However, the red cell and platelet types are found only as quite large progenitor stem cells more likened to the 'Gingerbread Mom' in the Nutcraker, hatching out little ones by lifting the hem of her skirt. Not many mature RBC or platelets are seen in the marrow because they tend to be released to the general circulation - the marrow won't function well if it is crowded or compacted- as RBC production is often held in a state of suspended animation, a slumber broken only by the whiff of erythropoetin, a hormone produced, stored, and released by the zona glomerulosa of the kidney(s) in response to a decreasing trend in the oxygen-carbon dioxide equilibrium.
Bone marrow depression is evaluated with a procedure that visually (stained microscopic slides) examines the contents and basically appears as an overall decrease in the numbers or functional appearance of the progenitor blast cells and can be as a result of anything that has a toxic effect on the Biology of these unique cellular organelles (not organs but then they aren't exactly cells, either)
Ionizing radiation -intentional (prior to bone marrow transplant) or unintentional (Chernobyl) will negatively alter marrow cellularity as will many chemicals such as lead salts, chloramphenicol, and benzene-like solvents - the term aplastic anemia is used to describe a quite problematic result of such exposure when mature red blood cells numbers are so very low and new ones aren't being successfully produced and released to the circulation.
Wiki User
∙ 11y ago
Wiki User
∙ 11y agoaplastic anemia
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What is the soft tissue at the center of bones known as?
The soft tissue in the center of bones is known as bone marrow.
A fatal condition in which the heart cannot pump adequate amounts of blood to tissues and organs is known as?
A decreased supply of oxygen to tissue is known as hypoxia.
Procedure used to obtain a sample of bone marrow for study?
This procedure is known as a bone marrow biopsy - A needle puncture to obtain a sample of bone marrow, usually from the ilium, for study; used to diagnose, stage, and monitor disease and condition of the blood cells
What is a primary bone marrow cell type that remains actively mitotic?
The primary bone marrow cell type that remains actively mitotic is known as the hemocytoblast.Osteocytes
What is the success of a bone marrow transplantation?
A bone marrow transplant takes a donor’s healthy blood-forming cells and puts them into the patient’s bloodstream, where they begin to grow and make healthy red blood cells, white blood cells and platelets. Patients receive high doses of chemotherapy to prepare their body for the transplant. Then on transplant day, the patient receives the donated cells in a process that is like getting blood or medicine through an intravenous (IV) catheter, or tube.
Is Myelophthisic anemia the same as leukoerythroblastic anemia?
A myelophthisic anemia is the displacement of the bone marrow into the peripheral circulation by a disease such as metastasis of the bone marrow. This leads to the presence of nucleated RBCs and immature myeloid cells in the peripheral blood. Under microscopy, this is known as "leukoerythroblastic smear."
What type of anemia is a condition characterized by an inadequate number of circulating red blood cells is known as what anemia?
Hemolytic anemia
What condition is the most nutrition responsive?
The condition that is known for being the most nutrition responsive is iron- deficiency anemia. This also apples to sickle-cell anemia.
What condition is a blood disorder also known as cooley's anemia?
beta thalassemia
What is the gene responsible for the condition known as sickle cell anemia demonstrate?
Incomplete dominance.
What condition do i have when inflammation in my bones and bone marrow?
Inflammation of the bones and bone marrow is known as osteomyelitis. This is a severe infection that may require long-term treatment.
What is aplastic anemia?
Aplastic anemia is a condition where bone marrow does not produce sufficient new cells to replenish blood cells. The term 'aplastic' means the marrow suffers from an aplasia that renders it unable to function properly. Anemia is the condition of having fewer red blood cells than normal, or fewer than needed to function properly. Typically, anemia refers to low red blood cell counts, but aplastic anemia patients have lower counts of all three blood cell types: red blood cells, white blood cells, and platelets. copied from wikipedia
What is a blood disorder also known as cooley's anemia?
Thalassemis is a blood disorder also known as cooley's anemia. It is also known as Mediterranean anemia.
Is depression a sickness?
Depression is a mental illness that can happen to really anyone and can cause both mental and physical symptoms.
What illness can be cured with REVLIMID?
REVLIMID, otherwise known as Lenalidomide, is a prescription drug used to treat anemia caused by myelodysplastic syndrome, a disease where bone marrow in the body does not make enough blood cells.
What is known as harvesting bone marrow and receiving it later as a bone marrow transplant?
Autologous bone marrow transplant
What is the soft tissue at the center of bones known as?
The soft tissue in the center of bones is known as bone marrow.
