answersLogoWhite

0

In humans, the bone marrow - that virtual space within larger bones of the skeletal system - primarily serves as non-distensible, temperature, and hemodynamically-stable 'nursery' for the hematopoetic (RBC-red blood cells) and megakaryocytic(platelets) cell lines. While other fully-maturated cells of the monocytic, lymphocytic, and neutrophylic (immune system) - are often found there, too, they are typically observed as fully mature cells going about their purposeful migrations as they easily slip through membranes, exploring and ridding the body for foreign invaders, such as parasites, viruses, bacteria, fungi, and debris. However, the red cell and platelet types are found only as quite large progenitor stem cells more likened to the 'Gingerbread Mom' in the Nutcraker, hatching out little ones by lifting the hem of her skirt. Not many mature RBC or platelets are seen in the marrow because they tend to be released to the general circulation - the marrow won't function well if it is crowded or compacted- as RBC production is often held in a state of suspended animation, a slumber broken only by the whiff of erythropoetin, a hormone produced, stored, and released by the zona glomerulosa of the kidney(s) in response to a decreasing trend in the oxygen-carbon dioxide equilibrium.

Bone marrow depression is evaluated with a procedure that visually (stained microscopic slides) examines the contents and basically appears as an overall decrease in the numbers or functional appearance of the progenitor blast cells and can be as a result of anything that has a toxic effect on the Biology of these unique cellular organelles (not organs but then they aren't exactly cells, either)

Ionizing radiation -intentional (prior to bone marrow transplant) or unintentional (Chernobyl) will negatively alter marrow cellularity as will many chemicals such as lead salts, chloramphenicol, and benzene-like solvents - the term aplastic anemia is used to describe a quite problematic result of such exposure when mature red blood cells numbers are so very low and new ones aren't being successfully produced and released to the circulation.

User Avatar

Wiki User

13y ago

What else can I help you with?

Related Questions

What type of anemia is a condition characterized by an inadequate number of circulating red blood cells is known as what anemia?

The condition characterized by an inadequate number of circulating red blood cells is known as hypoproliferative anemia. This can be caused by various factors such as nutrient deficiencies, bone marrow disorders, or chronic diseases.


Is Myelophthisic anemia the same as leukoerythroblastic anemia?

A myelophthisic anemia is the displacement of the bone marrow into the peripheral circulation by a disease such as metastasis of the bone marrow. This leads to the presence of nucleated RBCs and immature myeloid cells in the peripheral blood. Under microscopy, this is known as "leukoerythroblastic smear."


When your bone marrow stops its functions is it fatal?

Yes, if the bone marrow stops functioning completely, it can be fatal. The bone marrow is responsible for producing blood cells, and without a functioning bone marrow, the body cannot make enough red blood cells, white blood cells, and platelets to sustain life. This condition is known as aplastic anemia.


What condition is the most nutrition responsive?

The condition that is known for being the most nutrition responsive is iron- deficiency anemia. This also apples to sickle-cell anemia.


What condition is a blood disorder also known as cooley's anemia?

beta thalassemia


What is marrow hypoplasia?

Marrow hypoplasia, also known as aplastic anemia, is a condition where the bone marrow does not produce enough blood cells, including red blood cells, white blood cells, and platelets. This can result in symptoms like fatigue, paleness, frequent infections, and easy bruising. Treatment may involve medications, blood transfusions, and sometimes a bone marrow transplant.


What causes marrow to stop producing white and red blood cells?

Factors such as certain types of cancer, chemotherapy, radiation therapy, certain medications, infections, autoimmune disorders, and inherited conditions can cause the bone marrow to stop producing white and red blood cells. This condition is known as bone marrow failure or aplastic anemia.


What condition do i have when inflammation in my bones and bone marrow?

Inflammation of the bones and bone marrow is known as osteomyelitis. This is a severe infection that may require long-term treatment.


What is aplastic anemia?

Aplastic anemia is a condition where bone marrow does not produce sufficient new cells to replenish blood cells. The term 'aplastic' means the marrow suffers from an aplasia that renders it unable to function properly. Anemia is the condition of having fewer red blood cells than normal, or fewer than needed to function properly. Typically, anemia refers to low red blood cell counts, but aplastic anemia patients have lower counts of all three blood cell types: red blood cells, white blood cells, and platelets. copied from wikipedia


Can yellow marrow revert to red marrow?

Yes, yellow marrow can revert to red marrow in certain situations such as severe anemia or during times of increased demand for blood cell production. This process is known as reconversion and can occur in response to the body's need for more red blood cells.


Is depression a sickness?

Depression is a mental illness that can happen to really anyone and can cause both mental and physical symptoms.


What is a blood disorder also known as cooley's anemia?

Thalassemis is a blood disorder also known as cooley's anemia. It is also known as Mediterranean anemia.