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They like to use that analogy when talking about the individual strands of DNA (with the A C G T to distiguish them by using diffrent colored beads) when they are not twisted together to form the double helix. In general DNA could be referred to a twisted up latter.

Beads on a string refers to the arrangement of nucleosomes along chromatin fibers. The beads are the nucleosomes whereas the string is the linker DNA. Nucleosomes are the basic unit of chromatin structure.

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