a deletion of 2 nucleotides
Yes, if an enzyme necessary for polypeptide production is absent, the process may be disrupted. This could potentially lead to errors in translation, such as misincorporation of incorrect amino acids, which can result in a mutation in the polypeptide sequence.
The type of mutation that stops the translation of a protein is a nonsense mutation. This occurs when a base substitution (point mutation) results in a STOP codon and thus stops translation of the sequence into a protein.
A mutation in which a single base is added to or deleted from DNA is called an insertion or deletion mutation, also known as an indel mutation. This can lead to a shift in the reading frame during translation, causing significant changes in the resulting protein sequence and potentially leading to functional consequences.
This is an example of a frameshift mutation, where the reading frame of the genetic code is shifted due to an addition or deletion of nucleotides. This can lead to a completely different sequence of codons being read during translation, potentially resulting in a non-functional protein being produced.
There are three categories of point mutations:Nonsense - the mutated codon is now a stop codon, severely truncating the polypeptide. The protein will no longer function.Missense - the mutated codon now codes for a different amino acid, which alters the structure of the polypeptide. If the protein is still functional, it may be inhibited by its different structure, seen in sickle cell anemia. The changed polypeptide may also benefit the organism with a positive phenotype, which fuels evolution.Silent - because different arrangements of bases can code for the same amino acid, a mutated codon could code for the same amino acid as before. Effectively, the mutation did not change anything about the polypeptide ― hence, it is "silent."
Yes, if an enzyme necessary for polypeptide production is absent, the process may be disrupted. This could potentially lead to errors in translation, such as misincorporation of incorrect amino acids, which can result in a mutation in the polypeptide sequence.
The type of mutation that stops the translation of a protein is a nonsense mutation. This occurs when a base substitution (point mutation) results in a STOP codon and thus stops translation of the sequence into a protein.
Yes, a point mutation will cause the cell to make an incompelete polypeptide chain that is non-functional, if the mutation results in a stop codon. This type of a mutation is also called as the Nonsense Mutation.
codon
Yes it will.
An inactive/other active protein as a polypeptide that is incomplete will not fold properly. You could get a deleterious mutation that destroys protein product, such as Huntington's disease, or a paint mutation that, in heterozygous condition, such as sickle cell trait, is beneficial.
A point mutation is best described by this statement. Point mutations occur when there is a change in a single nucleotide base in the DNA sequence, which can lead to changes in the corresponding amino acid sequence of a polypeptide during protein synthesis.
Missence mutation
Missense mutation: changes one sense codon to another, resulting in incorporation of amino acid.Nonsense mutation: changes a sense codon into a stop (or nonsense) codon, resulting in premature termination.
A mutation in which a single base is added to or deleted from DNA is called an insertion or deletion mutation, also known as an indel mutation. This can lead to a shift in the reading frame during translation, causing significant changes in the resulting protein sequence and potentially leading to functional consequences.
A frameshift mutation is introduced by adding or deleting nucleotides in a DNA sequence that is not a multiple of three. This results in a shift in the reading frame during translation, leading to a completely different amino acid sequence downstream of the mutation. Frameshift mutations can have drastic effects on the resulting protein structure and function.
a silent mutation.