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Hans Krebs and Kurt Henseleit in 1932

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16y ago

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Which compounds involved in the urea cycle are linked to the Krebs cycle?

Fumarate and aspartate are the compounds that are linked between the urea cycle and the Krebs cycle. Fumarate from the Krebs cycle can be converted to arginine in the urea cycle, while aspartate from the urea cycle can be converted to oxaloacetate in the Krebs cycle.


Where does the urea cycle take place in the body?

The urea cycle takes place in the liver.


What compound is regenerated in the urea cycle?

The compound regenerated in the urea cycle is ornithine. This compound allows the cycle to continue by combining with carbamoyl phosphate to form citrulline, which is then further processed to produce urea.


Where does urea cycle takes place?

ammonium ion, which is the end product of amino acid degradation, is toxic if allowed to accumulate. the urea cycle is a pathway that detoxifies the ammonium ions by converting it to urea - which is then transported to the kidneys to form urine... the function is to remove nitrogen waste from the body and avoid toxicity


Does oxaloacetate contribute to the urea cycle?

Yes, oxaloacetate contributes to the urea cycle by combining with carbamoyl phosphate to form citrulline. This is an important step in the conversion of ammonia into urea for excretion.


What converts ammonia to urea?

The urea cycle, which occurs in the liver, converts ammonia to urea. The urea cycle involves a series of reactions that ultimately result in the production of urea, which is then excreted by the kidneys in urine. This process helps to safely remove excess ammonia from the body.


Describe the sequence of events that take place to remove ammonia from the body?

Ammonia is detoxified in the liver to form urea, which is then excreted in the urine by the kidneys. This process occurs in the urea cycle, also known as the ornithine cycle. The urea cycle involves a series of enzymatic reactions that convert ammonia into urea, making it less toxic for the body.


What is the significance of urea cycle in the formation of amino acids?

Over all reaction of Urea Cycle. NH4 + CO2 + Aspartate + 3 ATP ---> Urea + Fumarate + 2 ADP + 2 Pi + AMP + PPi Formula is formed.


Excess nitrogen is converted in what by the liver?

Excess nitrogen is converted into urea by the liver through a process called the urea cycle. Urea is then excreted in urine by the kidneys to maintain nitrogen balance in the body.


What enzymes activate the formation of the urea?

The formation of urea in the liver occurs through the urea cycle, primarily involving several key enzymes. These include carbamoyl phosphate synthetase I, which initiates the cycle by converting ammonia and bicarbonate into carbamoyl phosphate, followed by ornithine transcarbamylase, argininosuccinate synthetase, and argininosuccinate lyase. Finally, arginase catalyzes the conversion of arginine to urea and ornithine, completing the cycle.


What is the process called when urea is formed?

It's called the Bosch-Meiser urea process. See https://en.wikipedia.org/wiki/Urea


Where does the conversion of amino-acid to urea take place?

The conversion of amino acids to urea primarily takes place in the liver. This process mainly occurs in the hepatocytes (liver cells) as part of the urea cycle, also known as the ornithine cycle. Urea is then released into the bloodstream and eventually excreted by the kidneys in the urine.