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RNA has a 2' OH group because it helps stabilize the molecule's structure and allows for flexibility in folding, which is important for its various functions in gene expression and protein synthesis.

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What is the significance of the 3' OH group in RNA synthesis?

The 3' OH group in RNA synthesis is important because it allows the addition of new nucleotides to the growing RNA strand. This group acts as a site for the formation of phosphodiester bonds between nucleotides, enabling the sequential assembly of the RNA molecule.


Why is RNA readily hydrolyzed by acid solutions?

RNA contains a ribose sugar that is vulnerable to hydrolysis when exposed to acid solutions. The acid can protonate the hydroxyl group at the C2 position of the ribose, leading to a breakage of the phosphodiester bond between nucleotides in the RNA chain. This results in the degradation of the RNA molecule.


What is a sugar group of RNA?

A sugar group in RNA refers to the ribose sugar molecule that forms the backbone of the RNA molecule. It is a crucial component that helps make up the structure of RNA, along with the phosphate group and nitrogenous bases. The ribose sugar in RNA differs from the deoxyribose sugar in DNA by having an extra hydroxyl (-OH) group.


Which molecules are components of an RNA nucleotide?

An RNA nucleotide is composed of three main components: a ribose sugar, a phosphate group, and a nitrogenous base. The ribose sugar distinguishes RNA from DNA, as it contains an -OH group on the 2' carbon. The nitrogenous bases in RNA include adenine (A), uracil (U), cytosine (C), and guanine (G). These components combine to form the building blocks of RNA molecules.


Why RNA extraction is difficult?

RNA itself difficult to handle because of its unstable nature. Unlike DNA, RNA has free 2'-OH group in their ribose sugar that make them highly reactive. Other than this, RNAse contamination is everywhere (during isolation RNAase from our skin can kill RNA).


RNA is chemically similar to DNA except that the sugar in RNA has an additional?

The ribose sugar in RNA has an additional oxygen, which holds a hydrogen, thus making it a hydroxyl group.


Does DNA have a 2' OH group in its structure?

No, DNA does not have a 2' OH group in its structure.


What is the difference between ribonucleotides and deoxyribonucleotides?

The main difference is the presence of a hydroxyl (-OH) group on the 2' carbon of the ribose sugar in ribonucleotides, whereas deoxyribonucleotides lack this hydroxyl group. This small difference affects the stability and structure of RNA and DNA molecules. Ribonucleotides are used for RNA synthesis while deoxyribonucleotides are used for DNA synthesis.


Does rna have a phosphate group or a hydroxyl group?

RNA has both a phosphate group in its backbone and a hydroxyl group on the ribose sugar in its structure. The phosphate group connects the nucleotides in RNA's backbone, while the hydroxyl group distinguishes RNA from DNA, which has a hydrogen atom in its place.


How is RNA difernt from DNA?

dna has adenine, thymine guanine, and cytosine as its bases. dna is double stranded. dna is made of deoxyribose. in dna H attatches to its 2'. in rna uracil replaces thymine. rna is single stranded. rna is made of ribose. in rna OH attaches to its 2'.


Is deoxyribose sugar DNA?

Yes DNA has deoxy-ribose sugar in their backbone (hence they are Deoxy ribo Nucleic Acids). whereas, RNA has the oxyribose sugar where the 2'-OH group intact.


What is the significance of the 2' hydroxyl group in RNA structure and function?

The 2' hydroxyl group in RNA is important for its structure and function because it affects the stability and flexibility of the molecule. This group allows RNA to fold into specific shapes and interact with other molecules, enabling it to carry out its various biological functions, such as protein synthesis and gene regulation.