That depends on what you mean by lethal. If you mean e.g. the gene for Huntington's disease than this is because the carrier is likely to pass on their genes before death as it only manifests later on in life. Unless the gene causes the carrier to die before they reproduce - it will stay in the gene pool. Would you kill someone because they had a genetic disorder or not let them reproduce?
It's an autosomal dominant disease. Source: http://en.wikipedia.org/wiki/Achondroplasia
Dominant lethal is a genetic trait. If the genome of an individual has the trait, it is expressed and makes it impossible for the individual to have descendants. Its effects cause foetal or embryonic death.
Intuitively, natural selection should eliminate these lethal genetic disorders from the population.....However, natural selection does not act on the genotype of an individual, but on the phenotype. Many of these lethal genetic disorders are the product of two "recessive alleles" that were masked in the parents with a "dominant allele."
Lethal dominant alleles are less common than lethal recessive alleles because individuals with lethal dominant alleles typically die before they can pass on the harmful gene to their offspring, reducing the frequency of the allele in the population. In contrast, individuals with lethal recessive alleles can carry the gene without showing symptoms, allowing the allele to persist in the population through carriers who can pass it on to their offspring.
A lethal dominant gene prohibits the organism from reproducing irregardless of the paired gene, so it is removed from the gene pool as soon as it appears. A lethal recessive gene, on the other hand, does not prevent reproduction unless it is paired with another lethal recessive, so it may be passed down through many generations before becoming paired and preventing reproduction.
page 314 Huntington's disease is lethal GENETIC DISORDER caused by a rare dominant allele. It's not a chromosonal disease, it is a genetic disorder. D
Huntington's disease is an example of a lethal dominant mutation. It is a neurodegenerative disorder caused by a dominant mutation in the HTT gene, leading to progressive loss of motor and cognitive functions, eventually resulting in death.
Huntington's disease, where the lethal allele expresses itself very late in an individuals life. Persons carrying the dominant lethal allele does not become aware of the disease until after their reproductive age. Thus, they pass the lethal allele to their children without knowing and the allele persists.
It's an autosomal dominant disease. Source: http://en.wikipedia.org/wiki/Achondroplasia
Dominant lethal is a genetic trait. If the genome of an individual has the trait, it is expressed and makes it impossible for the individual to have descendants. Its effects cause foetal or embryonic death.
Intuitively, natural selection should eliminate these lethal genetic disorders from the population.....However, natural selection does not act on the genotype of an individual, but on the phenotype. Many of these lethal genetic disorders are the product of two "recessive alleles" that were masked in the parents with a "dominant allele."
Lethal dominant alleles are less common than lethal recessive alleles because individuals with lethal dominant alleles typically die before they can pass on the harmful gene to their offspring, reducing the frequency of the allele in the population. In contrast, individuals with lethal recessive alleles can carry the gene without showing symptoms, allowing the allele to persist in the population through carriers who can pass it on to their offspring.
Cystic fibrosis it is characterized by thick mucus in the lungs
Then HD would disappear after 1 generation. No one would be alive with HD that could pass it down to their children.
I believe it is an autosomal recessive disorder, meaning it is only apparent with a homozygous recessive genotype. But i could be wrong (i loathe biology). oh really?
yes, if untreated
This means that you have a genetic disease where as your DNA suppresses certain proteins in your body, thus either 1: giving you a deadly mutation somewhere on the body or 2: killing you I think?