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In chromosomes there is a lot of non-coding DNA and a small modification might not cause any problem while in genes if you make a small change it might cause an enzyme to be defective and not work properly or not work at all and therefore a pathway might be disrupted and cause a disorder.

So both of them might be dangerous, but the gene mutation as a much higher probability of being it.

Genes and Chromosomes Essentially represent the same entity, the Unit of Genetic Expression.

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12y ago
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13y ago

They cause diseases birth defects miscarriages and cancer cells

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14y ago

A gene is a section of a chromosome. So if a gene has a mutation, so does a chromosome.

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12y ago

They can both cause serious genetic disorders and can be lethal.

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Q: Why are chromosome mutations potentially more serious than gene mutations?
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How do chromosome mutations affect an individual?

Chromosome mutations can result in changes in the number of chromosomes in a cell or changes in the structure of a chromosome. Unlike a gene mutation which alters a single gene or larger segment of DNA on a chromosome, chromosome mutations change and impact the entire chromosome.


Mutation is any change in a gene or chromosome?

mutations


What chromosome is the gene of bipolar on?

bipolar susceptibility can be linked to small mutations in chromosomes 4,13,15,18, and 22.


Is cystic fibrosis monosmy or trisomy?

Neither. Cystic fibrosis is caused by mutations in the CFTR gene located on chromosome 7. It is not caused by the absence or addition of a chromosome.


What is the etiology of marfan syndrome?

The etiology of marfan syndrome would be the mutations in the protein FBN1 in the gene chromosome 15.


What gene or chromosome is affected by Crouzon Syndrome disorder?

Crouzon Syndrome is caused by mutations in the FGFR2 gene, which is located on chromosome 10. These mutations disrupt the function of the FGFR2 protein, leading to abnormal development of the skull and face.


Why is a gene mutation more serious what its at the beginning?

More serious than what? Mutations happen all the time and have done so.


What is the difference between gene and chromosomal mutation?

A gene mutation is a permanent change in the DNA sequence that makes up a gene. Mutations range in size from a single DNA building block (DNA base) to a large segment of a chromosome. A chromosomal mutation is a mutation involving a long segment of DNA, it is a any change in the structure or arrangement of the chromosomes. These mutations can involve deletions, insertions, or inversions of sections of DNA. In some cases, deleted sections may attach to other chromosomes, disrupting both the chromosomes that loses the DNA and the one that gains it.It is also referred to as a chromosomal rearrangement The differences between Gene mutation and Chromosome mutation are ; 1- Chromosome mutations involve changes in the structure of a chromosome OR the loss or gain of a chromosome while Gene mutations involve a change in the nucleotide -base sequence of a gene on a DNA molecule. 2- Chromosomal mutations are changes in the structure or the numbers of chromosomes (a gain or loss). Gene mutations involve changes in the nucleotide sequence of the DNA molecule. 3-A gene mutation is a permanent change in the DNA sequence that makes up a gene. Mutations range in size from a single DNA building block (DNA base) to a large segment of a chromosome while a chromosomal mutation is a mutation involving a long segment of DNA, it is a any change in the structure or arrangement of the chromosomes. These mutations can involve deletions, insertions, or inversions of sections of DNA. In some cases, deleted sections may attach to other chromosomes, disrupting both the chromosomes that loses the DNA and the one that gains it.It is also referred to as a chromosomal rearrangement 4-gene mutation is just a substitute in any old random nucleotide for any old random nucleotide chromosome mutation is missing of chromosome or +1 chromosome (down's syndrome).


What characteristics does an abnormal genetic test have?

An abnormal chromosome analysis report will include the total number of chromosomes and will identify the abnormality found. Tests for gene mutations will report the mutations found.


What is gene rearrangement?

Gene rearrangement actually means the rearrangement of gene in chromosomes. This can occur through 3 different ways which are inversion, translocation and transposition. These can definitely alter the chromosome and cause mutations to occur.


What is gene-rearrangement?

Gene rearrangement actually means the rearrangement of gene in chromosomes. This can occur through 3 different ways which are inversion, translocation and transposition. These can definitely alter the chromosome and cause mutations to occur.


What various types of genetic material in order from simplest to most complex?

nucleus → chromosome → gene