Gaps left at the 5' end of the lagging strand because of the need for a 3' onto which nucleotides can attach
Well in eukaryotic cells each chromosome has a telomere on each end (to prevent it from unraveling), but I'm not 100% certain that these telomeres are identical although they contain very long repetitions of the same nucleotides. But in bacteria the chromosome is ring shaped and is all genes (there are no noncoding sequences, e.g. centromeres, telomeres, introns, pseudogenes, transposons) so there are no identical parts.
A telomere is the structure at each end of a chromosome. It consists of an area of highly repeated DNA combined with protein. Its main function is to protect the end of the chromosome.Telomeres are instrumental in enabling the cells to divide and replicate. But as we grow older these tips wear out and shorten much like the shoelace caps. When they get too short, we get diseases and die. The three Nobel Prize winners found this as they were looking for a cure for cancer.
There are two telomeres for each chromosome, so you need to figure out how many chromosomes there are at each stage and multiply that by two. G1-- growth phase: 14 chromosomes = 28 telomeres G2-- growth phase after replication in S phase: 28 chromosomes= 56 telomeres Mitotic Prophase-- before cell division, nuclear membrane disappears: 28 chromosomes= 56 telomeres Mitotic telophase-- nuclei separate: 14 chromosomes = 28 telomeres
The telomere is the protective cap of DNA on the tip of chromosomes. You lose a small amount of these telomeres each time the cell divides. Eventually the telomeres be lost as you age. Short chromosomes because of lack telomeres are one reason aging occurs.
Human chromosomes are made up of chromatin, which is DNA wrapped around associated proteins called histones. Each chromosome has a single centromere joining the two chromatids. Telomeres are found at either end of the chromosome. They do not code for RNA, they protect the DNA from degradation during replication.
centromere, histone proteins, telomeres
Eukaryotic chromosomes are formed primarily of chromatids and telomeres
Telomeres solve the end replication problem by extending the 3' end of the chromosome. Without them, the 3' end can't be replicated since replication is 5' to 3'.
Actually the genes on a chromosome closest to the telomeres are the most unstable because they can unravel.
Well in eukaryotic cells each chromosome has a telomere on each end (to prevent it from unraveling), but I'm not 100% certain that these telomeres are identical although they contain very long repetitions of the same nucleotides. But in bacteria the chromosome is ring shaped and is all genes (there are no noncoding sequences, e.g. centromeres, telomeres, introns, pseudogenes, transposons) so there are no identical parts.
Telomeres shorten with each cellular replication; telomere length is inversely proportional to age. While telomere extension does tend to make cells "young again", telomere extension is problematic for a treatment for age because many kinds of cancer replicate indefinitely due in part to the fact they have overactive telomerase, a protein that extends the telomeres. Until the link between cancer and telomeres is understood, telomere extension therapy will not be feasible.
A telomere is the structure at each end of a chromosome. It consists of an area of highly repeated DNA combined with protein. Its main function is to protect the end of the chromosome.Telomeres are instrumental in enabling the cells to divide and replicate. But as we grow older these tips wear out and shorten much like the shoelace caps. When they get too short, we get diseases and die. The three Nobel Prize winners found this as they were looking for a cure for cancer.
There are two telomeres for each chromosome, so you need to figure out how many chromosomes there are at each stage and multiply that by two. G1-- growth phase: 14 chromosomes = 28 telomeres G2-- growth phase after replication in S phase: 28 chromosomes= 56 telomeres Mitotic Prophase-- before cell division, nuclear membrane disappears: 28 chromosomes= 56 telomeres Mitotic telophase-- nuclei separate: 14 chromosomes = 28 telomeres
The telomere is the protective cap of DNA on the tip of chromosomes. You lose a small amount of these telomeres each time the cell divides. Eventually the telomeres be lost as you age. Short chromosomes because of lack telomeres are one reason aging occurs.
Chromosomes consist of two arms that extend out from a specialized region of DNA , called Centromere. Centromere or primary constriction gives a particular shape to chromosomes due to its position. The chromosome extremities or terminal regions on either side are called telomeres.
the nucleotides at the terminal ends will be removed due to exonuclease activity of DNase present in the cells of the eukaryotes.and therefore the DNA strand will get shortened.
Yes. We all begin as 1 cell and as it divides the telomeres become shorter. Larger people have more cells than smaller people and therefore have shorter telomeres.