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Why is B-DNA more stable than A-DNA in solution please explain in detail?
Wiki User
∙ 12y ago
Because of the stability of its riboses. In A-DNA there is a 3C- in Endo position which makes the phosphate near the upper phosphate. This produces more repulsion between chains and it could be a reason of why is more unstable A than B.
In B-DNA the 3C is in Exo position ( C2 is in ENDO) and is because of that that phosphates are more farther in these conformation, allowing to get more stable interactions between chains.
Hope it helps!!
Robert Ramirez
Wiki User
∙ 12y ago
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